| 1 | |  CD Diocesano | 30 | 20 | 3 | 7 | 61 | 30 | 31 | 63 | B13:00 | 24/04/22 | R 30  SP Villafranca 1 CD Diocesano 1 M18:30 | 14/04/22 | R 29 CD Diocesano 1 CD Azuaga 2 G13:00 | 10/04/22 | R 28 CD Calamonte 1 CD Diocesano 3 G13:00 | 03/04/22 | R 27 CD Diocesano 3 CF Trujillo 1 G13:00 | 27/03/22 | R 26 UP Plasencia 0 CD Diocesano 4 G14:00 | 20/03/22 | R 25 CD Diocesano 3 EMD Aceuchal 0 |
| 2 | |  Moralo CP | 30 | 14 | 10 | 6 | 39 | 19 | 20 | 52 | M19:00 | 24/04/22 | R 30 Moralo CP 0 AD Llerenense 1 M19:00 | 17/04/22 | R 29 Arroyo CP 1 Moralo CP 0 B18:30 | 10/04/22 | R 28 SP Villafranca 0 Moralo CP 0 G19:00 | 03/04/22 | R 27 Moralo CP 2 CD Don Alvaro 0 |
| 3 | |  AD Llerenense | 30 | 13 | 12 | 5 | 44 | 32 | 12 | 51 | G19:00 | 24/04/22 | R 30 Moralo CP 0 AD Llerenense 1 B18:30 | 14/04/22 | R 29 AD Llerenense 1 SP Villafranca 1 B19:00 | 10/04/22 | R 28 CD Azuaga 1 AD Llerenense 1 G19:00 | 03/04/22 | R 27 AD Llerenense 1 CD Calamonte 0 |
| 4 | |  Jerez CF | 30 | 14 | 7 | 9 | 38 | 30 | 8 | 49 | G19:00 | 24/04/22 | R 30 Jerez CF 1 Arroyo CP 0 B19:30 | 17/04/22 | R 29 CD Don Alvaro 1 Jerez CF 1 G18:00 | 10/04/22 | R 28 Jerez CF 2 Extremadura UD B 0 G18:00 | 03/04/22 | R 27 CD Badajoz B 1 Jerez CF 2 G19:00 | 27/03/22 | R 26 Jerez CF 3 CD Miajadas 0 |
| 5 | |  CF Trujillo | 30 | 12 | 12 | 6 | 40 | 27 | 13 | 48 | G19:00 | 24/04/22 | R 30 CF Trujillo 1 CD Badajoz B 0 G13:00 | 14/04/22 | R 29 CD Miajadas 2 CF Trujillo 3 B18:30 | 10/04/22 | R 28 CF Trujillo 1 Olivenza FC 1 M13:00 | 03/04/22 | R 27 CD Diocesano 3 CF Trujillo 1 B13:00 | 27/03/22 | R 26 CF Trujillo 3 AD Llerenense 3 B19:00 | 20/03/22 | R 25 SP Villafranca 0 CF Trujillo 0 |
| 6 | |  CD Azuaga | 30 | 12 | 12 | 6 | 41 | 31 | 10 | 48 | G19:00 | 24/04/22 | R 30 CD Azuaga 1 Olivenza FC 0 G18:30 | 14/04/22 | R 29 CD Diocesano 1 CD Azuaga 2 B19:00 | 10/04/22 | R 28 CD Azuaga 1 AD Llerenense 1 G18:30 | 03/04/22 | R 27 SP Villafranca 1 CD Azuaga 5 B17:30 | 27/03/22 | R 26 CD Azuaga 0 Moralo CP 0 B14:00 | 20/03/22 | R 25 CD Azuaga 1 CD Calamonte 1 |
| 7 | |  Arroyo CP | 30 | 12 | 12 | 6 | 40 | 30 | 10 | 48 | M19:00 | 24/04/22 | R 30 Jerez CF 1 Arroyo CP 0 G19:00 | 17/04/22 | R 29 Arroyo CP 1 Moralo CP 0 B19:00 | 10/04/22 | R 28 Arroyo CP 1 CD Don Alvaro 1 G18:00 | 03/04/22 | R 27 Extremadura UD B 0 Arroyo CP 2 G19:00 | 27/03/22 | R 26 Arroyo CP 2 CD Badajoz B 1 |
| 8 | |  CD Calamonte | 30 | 11 | 10 | 9 | 35 | 33 | 2 | 43 | G19:00 | 24/04/22 | R 30 CD Calamonte 2 CD Miajadas 1 M20:30 | 14/04/22 | R 29 Olivenza FC 2 CD Calamonte 1 M13:00 | 10/04/22 | R 28 CD Calamonte 1 CD Diocesano 3 M19:00 | 03/04/22 | R 27 AD Llerenense 1 CD Calamonte 0 G13:00 | 27/03/22 | R 26 CD Calamonte 2 SP Villafranca 1 B14:00 | 20/03/22 | R 25 CD Azuaga 1 CD Calamonte 1 |
| 9 | |  UP Plasencia | 30 | 10 | 8 | 12 | 24 | 29 | -5 | 38 | G15:00 | 24/04/22 | R 30 UP Plasencia 2 Extremadura UD B 0 M18:00 | 16/04/22 | R 29 CD Badajoz B 2 UP Plasencia 0 B19:00 | 09/04/22 | R 28 UP Plasencia 0 CD Miajadas 0 G13:00 | 03/04/22 | R 27 Olivenza FC 1 UP Plasencia 2 M13:00 | 27/03/22 | R 26 UP Plasencia 0 CD Diocesano 4 M19:30 | 19/03/22 | R 25 AD Llerenense 2 UP Plasencia 1 |
| 10 | |  SP Villafranca | 30 | 9 | 10 | 11 | 27 | 30 | -3 | 37 | B13:00 | 24/04/22 | R 30 SP Villafranca 1 CD Diocesano 1 B18:30 | 14/04/22 | R 29 AD Llerenense 1 SP Villafranca 1 B18:30 | 10/04/22 | R 28 SP Villafranca 0 Moralo CP 0 M18:30 | 03/04/22 | R 27 SP Villafranca 1 CD Azuaga 5 M13:00 | 27/03/22 | R 26 CD Calamonte 2 SP Villafranca 1 B19:00 | 20/03/22 | R 25 SP Villafranca 0 CF Trujillo 0 |
| 11 | |  Olivenza FC | 30 | 7 | 12 | 11 | 31 | 35 | -4 | 33 | M19:00 | 24/04/22 | R 30 CD Azuaga 1 Olivenza FC 0 G20:30 | 14/04/22 | R 29 Olivenza FC 2 CD Calamonte 1 B18:30 | 10/04/22 | R 28 CF Trujillo 1 Olivenza FC 1 M13:00 | 03/04/22 | R 27 Olivenza FC 1 UP Plasencia 2 M19:00 | 27/03/22 | R 26 EMD Aceuchal 2 Olivenza FC 0 B22:30 | 23/03/22 | R 23 Olivenza FC 2 CD Don Alvaro 2 |
| 12 | |  CD Don Alvaro | 30 | 7 | 10 | 13 | 36 | 44 | -8 | 31 | G19:00 | 24/04/22 | R 30 EMD Aceuchal 1 CD Don Alvaro 3 B19:30 | 17/04/22 | R 29 CD Don Alvaro 1 Jerez CF 1 B19:00 | 10/04/22 | R 28 Arroyo CP 1 CD Don Alvaro 1 M19:00 | 03/04/22 | R 27 Moralo CP 2 CD Don Alvaro 0 G15:00 | 27/03/22 | R 26 CD Don Alvaro 2 Extremadura UD B 0 B22:30 | 23/03/22 | R 23 Olivenza FC 2 CD Don Alvaro 2 |
| 13 | |  CD Miajadas | 30 | 8 | 5 | 17 | 30 | 48 | -18 | 29 | M19:00 | 24/04/22 | R 30 CD Calamonte 2 CD Miajadas 1 M13:00 | 14/04/22 | R 29 CD Miajadas 2 CF Trujillo 3 B19:00 | 09/04/22 | R 28 UP Plasencia 0 CD Miajadas 0 M13:00 | 03/04/22 | R 27 CD Miajadas 1 EMD Aceuchal 3 M19:00 | 27/03/22 | R 26 Jerez CF 3 CD Miajadas 0 G14:00 | 20/03/22 | R 25 CD Miajadas 1 Arroyo CP 0 |
| 14 | |  EMD Aceuchal | 30 | 7 | 8 | 15 | 24 | 42 | -18 | 29 | M19:00 | 24/04/22 | R 30 EMD Aceuchal 1 CD Don Alvaro 3 G18:00 | 17/04/22 | R 29 Extremadura UD B 0 EMD Aceuchal 2 G19:00 | 10/04/22 | R 28 EMD Aceuchal 1 CD Badajoz B 0 G13:00 | 03/04/22 | R 27 CD Miajadas 1 EMD Aceuchal 3 G19:00 | 27/03/22 | R 26 EMD Aceuchal 2 Olivenza FC 0 M14:00 | 20/03/22 | R 25 CD Diocesano 3 EMD Aceuchal 0 |
| 15 | |  CD Badajoz B | 30 | 6 | 9 | 15 | 24 | 38 | -14 | 27 | M19:00 | 24/04/22 | R 30 CF Trujillo 1 CD Badajoz B 0 G18:00 | 16/04/22 | R 29 CD Badajoz B 2 UP Plasencia 0 M19:00 | 10/04/22 | R 28 EMD Aceuchal 1 CD Badajoz B 0 M18:00 | 03/04/22 | R 27 CD Badajoz B 1 Jerez CF 2 M19:00 | 27/03/22 | R 26 Arroyo CP 2 CD Badajoz B 1 B19:00 | 20/03/22 | R 25 CD Badajoz B 1 CD Don Alvaro 1 |
| 16 | |  Extremadura UD B | 30 | 6 | 4 | 20 | 18 | 54 | -36 | 0 | M15:00 | 24/04/22 | R 30 UP Plasencia 2 Extremadura UD B 0 M18:00 | 17/04/22 | R 29 Extremadura UD B 0 EMD Aceuchal 2 M18:00 | 10/04/22 | R 28 Jerez CF 2 Extremadura UD B 0 M18:00 | 03/04/22 | R 27 Extremadura UD B 0 Arroyo CP 2 M15:00 | 27/03/22 | R 26 CD Don Alvaro 2 Extremadura UD B 0 M16:00 | 20/03/22 | R 25 Moralo CP 2 Extremadura UD B 0 |
