| 1 | |  Recreativo Huelva | 32 | 24 | 5 | 3 | 57 | 20 | 37 | 77 | G14:00 | 13/03/22 | R 28  Recreativo Huelva 2 UD Los Barrios 0 B19:00 | 20/03/22 | R 29 CD Pozoblanco 1 Recreativo Huelva 1 G18:00 | 27/03/22 | R 30 Recreativo Huelva 1 AD Cartaya 0 B21:30 | 07/04/22 | R 32 Recreativo Huelva 1 Cordoba CF B 1 G19:30 | 17/04/22 | R 33 Recreativo Huelva 3 CD Cabecense 0 M13:00 | 24/04/22 | R 34 UD Tomares 3 Recreativo Huelva 2 |
| 2 | |  CD Utrera | 32 | 20 | 7 | 5 | 59 | 26 | 33 | 67 | G13:00 | 27/03/22 | R 30 CD Utrera 3 UD Los Barrios 0 M19:00 | 03/04/22 | R 31 CD Pozoblanco 3 CD Utrera 1 B19:00 | 09/04/22 | R 32 CD Utrera 0 AD Cartaya 0 B13:00 | 24/04/22 | R 34 CD Utrera 1 Cordoba CF B 1 G19:00 | 07/05/22 | R semifinal CD Utrera 2 CD Gerena 1 B13:00 | 15/05/22 | R final CD Utrera 1 CD Ciudad de Lucena 1 |
| 3 | |  Xerez | 32 | 18 | 8 | 6 | 50 | 24 | 26 | 62 | G19:00 | 27/03/22 | R 30 Xerez 1 CD Cabecense 0 G14:00 | 03/04/22 | R 31 Conil CF 0 Xerez 1 B19:00 | 09/04/22 | R 32 Xerez 1 CD Gerena 1 G13:00 | 14/04/22 | R 33 Sevilla FC C 0 Xerez 1 G13:00 | 24/04/22 | R 34 Xerez 2 Puente Genil FC 0 M13:00 | 07/05/22 | R semifinal Xerez 2 CD Ciudad de Lucena 3 |
| 4 | |  CD Ciudad de Lucena | 32 | 18 | 6 | 8 | 45 | 25 | 20 | 60 | M18:00 | 03/04/22 | R 31 Puente Genil FC 2 CD Ciudad de Lucena 1 G19:00 | 09/04/22 | R 32 CD Ciudad de Lucena 5 UD Los Barrios 0 G19:00 | 17/04/22 | R 33 CD Pozoblanco 0 CD Ciudad de Lucena 2 G13:00 | 24/04/22 | R 34 CD Ciudad de Lucena 1 AD Cartaya 0 G13:00 | 07/05/22 | R semifinal Xerez 2 CD Ciudad de Lucena 3 B13:00 | 15/05/22 | R final CD Utrera 1 CD Ciudad de Lucena 1 |
| 5 | |  CD Gerena | 32 | 18 | 4 | 10 | 53 | 31 | 22 | 58 | G13:00 | 27/03/22 | R 30 CD Rota 0 CD Gerena 1 G19:30 | 03/04/22 | R 31 CD Gerena 3 CA Antoniano 1 B19:00 | 09/04/22 | R 32 Xerez 1 CD Gerena 1 G20:00 | 17/04/22 | R 33 CD Gerena 6 Conil CF 0 G13:00 | 24/04/22 | R 34 CD Cabecense 0 CD Gerena 3 M19:00 | 07/05/22 | R semifinal CD Utrera 2 CD Gerena 1 |
| 6 | |  Cordoba CF B | 32 | 17 | 7 | 8 | 54 | 33 | 21 | 58 | G18:30 | 12/03/22 | R 28 Cordoba CF B 1 CD Pozoblanco 0 G19:00 | 19/03/22 | R 29 AD Cartaya 0 Cordoba CF B 1 M13:00 | 03/04/22 | R 31 CD Cabecense 4 Cordoba CF B 3 B21:30 | 07/04/22 | R 32 Recreativo Huelva 1 Cordoba CF B 1 G13:00 | 14/04/22 | R 33 Cordoba CF B 5 UD Tomares 1 B13:00 | 24/04/22 | R 34 CD Utrera 1 Cordoba CF B 1 |
| 7 | |  Puente Genil FC | 32 | 13 | 6 | 13 | 36 | 41 | -5 | 45 | M19:00 | 20/03/22 | R 29 Puente Genil FC 1 CD Utrera 2 B20:00 | 26/03/22 | R 30 AD Ceuta B 0 Puente Genil FC 0 G18:00 | 03/04/22 | R 31 Puente Genil FC 2 CD Ciudad de Lucena 1 B18:00 | 09/04/22 | R 32 CD Rota 1 Puente Genil FC 1 M19:00 | 17/04/22 | R 33 Puente Genil FC 0 CA Antoniano 1 M13:00 | 24/04/22 | R 34 Xerez 2 Puente Genil FC 0 |
| 8 | |  Sevilla FC C | 32 | 13 | 4 | 15 | 40 | 48 | -8 | 43 | G15:00 | 19/03/22 | R 29 Sevilla FC C 3 AD Ceuta B 0 G13:00 | 27/03/22 | R 30 CD Ciudad de Lucena 1 Sevilla FC C 2 M13:00 | 03/04/22 | R 31 Sevilla FC C 0 CD Rota 1 G13:00 | 09/04/22 | R 32 CA Antoniano 0 Sevilla FC C 1 M13:00 | 14/04/22 | R 33 Sevilla FC C 0 Xerez 1 G13:00 | 24/04/22 | R 34 Conil CF 2 Sevilla FC C 4 |
| 9 | |  AD Ceuta B | 32 | 9 | 10 | 13 | 26 | 39 | -13 | 37 | G20:00 | 12/03/22 | R 28 AD Ceuta B 2 CD Gerena 1 M15:00 | 19/03/22 | R 29 Sevilla FC C 3 AD Ceuta B 0 B20:00 | 26/03/22 | R 30 AD Ceuta B 0 Puente Genil FC 0 G18:00 | 03/04/22 | R 31 UD Los Barrios 0 AD Ceuta B 1 B18:30 | 09/04/22 | R 32 AD Ceuta B 1 CD Pozoblanco 1 M17:30 | 16/04/22 | R 33 AD Cartaya 2 AD Ceuta B 0 |
| 10 | |  CD Rota | 32 | 9 | 9 | 14 | 31 | 45 | -14 | 36 | M14:00 | 20/03/22 | R 29 Conil CF 3 CD Rota 1 M13:00 | 27/03/22 | R 30 CD Rota 0 CD Gerena 1 G13:00 | 03/04/22 | R 31 Sevilla FC C 0 CD Rota 1 B18:00 | 09/04/22 | R 32 CD Rota 1 Puente Genil FC 1 B13:00 | 14/04/22 | R 33 UD Los Barrios 1 CD Rota 1 G13:00 | 24/04/22 | R 34 CD Rota 3 CD Pozoblanco 1 |
| 11 | |  Conil CF | 32 | 10 | 6 | 16 | 30 | 49 | -19 | 36 | G14:00 | 20/03/22 | R 29 Conil CF 3 CD Rota 1 M18:00 | 27/03/22 | R 30 CA Antoniano 2 Conil CF 1 M14:00 | 03/04/22 | R 31 Conil CF 0 Xerez 1 B18:00 | 09/04/22 | R 32 Conil CF 1 CD Cabecense 1 M20:00 | 17/04/22 | R 33 CD Gerena 6 Conil CF 0 M13:00 | 24/04/22 | R 34 Conil CF 2 Sevilla FC C 4 |
| 12 | |  CA Antoniano | 32 | 8 | 10 | 14 | 29 | 35 | -6 | 34 | B20:00 | 20/03/22 | R 29 Xerez 1 CA Antoniano 1 G18:00 | 27/03/22 | R 30 CA Antoniano 2 Conil CF 1 M19:30 | 03/04/22 | R 31 CD Gerena 3 CA Antoniano 1 M13:00 | 09/04/22 | R 32 CA Antoniano 0 Sevilla FC C 1 G19:00 | 17/04/22 | R 33 Puente Genil FC 0 CA Antoniano 1 G13:00 | 24/04/22 | R 34 CA Antoniano 3 UD Los Barrios 0 |
| 13 | |  CD Pozoblanco | 32 | 8 | 10 | 14 | 37 | 49 | -12 | 34 | B19:00 | 20/03/22 | R 29 CD Pozoblanco 1 Recreativo Huelva 1 M13:00 | 27/03/22 | R 30 UD Tomares 3 CD Pozoblanco 2 G19:00 | 03/04/22 | R 31 CD Pozoblanco 3 CD Utrera 1 B18:30 | 09/04/22 | R 32 AD Ceuta B 1 CD Pozoblanco 1 M19:00 | 17/04/22 | R 33 CD Pozoblanco 0 CD Ciudad de Lucena 2 M13:00 | 24/04/22 | R 34 CD Rota 3 CD Pozoblanco 1 |
| 14 | |  AD Cartaya | 32 | 8 | 9 | 15 | 26 | 30 | -4 | 33 | M19:00 | 19/03/22 | R 29 AD Cartaya 0 Cordoba CF B 1 M18:00 | 27/03/22 | R 30 Recreativo Huelva 1 AD Cartaya 0 M18:00 | 03/04/22 | R 31 AD Cartaya 0 UD Tomares 2 B19:00 | 09/04/22 | R 32 CD Utrera 0 AD Cartaya 0 G17:30 | 16/04/22 | R 33 AD Cartaya 2 AD Ceuta B 0 M13:00 | 24/04/22 | R 34 CD Ciudad de Lucena 1 AD Cartaya 0 |
| 15 | |  UD Tomares | 32 | 9 | 4 | 19 | 27 | 46 | -19 | 31 | M14:00 | 13/03/22 | R 28 UD Tomares 0 Puente Genil FC 1 M19:00 | 20/03/22 | R 29 UD Los Barrios 2 UD Tomares 0 G13:00 | 27/03/22 | R 30 UD Tomares 3 CD Pozoblanco 2 G18:00 | 03/04/22 | R 31 AD Cartaya 0 UD Tomares 2 M13:00 | 14/04/22 | R 33 Cordoba CF B 5 UD Tomares 1 G13:00 | 24/04/22 | R 34 UD Tomares 3 Recreativo Huelva 2 |
| 16 | |  CD Cabecense | 32 | 6 | 5 | 21 | 25 | 51 | -26 | 23 | B20:30 | 13/03/22 | R 28 CA Antoniano 1 CD Cabecense 1 M19:00 | 27/03/22 | R 30 Xerez 1 CD Cabecense 0 G13:00 | 03/04/22 | R 31 CD Cabecense 4 Cordoba CF B 3 B18:00 | 09/04/22 | R 32 Conil CF 1 CD Cabecense 1 M19:30 | 17/04/22 | R 33 Recreativo Huelva 3 CD Cabecense 0 M13:00 | 24/04/22 | R 34 CD Cabecense 0 CD Gerena 3 |
| 17 | |  UD Los Barrios | 32 | 5 | 8 | 19 | 26 | 59 | -33 | 23 | G19:00 | 20/03/22 | R 29 UD Los Barrios 2 UD Tomares 0 M13:00 | 27/03/22 | R 30 CD Utrera 3 UD Los Barrios 0 M18:00 | 03/04/22 | R 31 UD Los Barrios 0 AD Ceuta B 1 M19:00 | 09/04/22 | R 32 CD Ciudad de Lucena 5 UD Los Barrios 0 B13:00 | 14/04/22 | R 33 UD Los Barrios 1 CD Rota 1 M13:00 | 24/04/22 | R 34 CA Antoniano 3 UD Los Barrios 0 |
