| 1 | |  FC Porto | 34 | 29 | 4 | 1 | 86 | 22 | 64 | 91 | G20:00 | 14/05/22 | R 34  FC Porto 2 Estoril Praia 0 G20:00 | 07/05/22 | R 33 Benfica Lisbon 0 FC Porto 1 G21:00 | 30/04/22 | R 32 FC Porto 4 FC Vizela 2 M20:00 | 25/04/22 | R 31 SC Braga 1 FC Porto 0 G22:30 | 16/04/22 | R 30 FC Porto 7 Portimonense SC 0 G20:00 | 10/04/22 | R 29 Vitoria Guimarares 0 FC Porto 1 |
| 2 | |  Sporting Lisbon | 34 | 27 | 4 | 3 | 73 | 23 | 50 | 85 | G22:30 | 14/05/22 | R 34 Sporting Lisbon 4 Santa Clara Azores 0 G22:30 | 07/05/22 | R 33 Portimonense SC 2 Sporting Lisbon 3 G22:30 | 01/05/22 | R 32 Sporting Lisbon 4 Gil Vicente Barcelos 1 G22:30 | 25/04/22 | R 31 Boavista Porto 0 Sporting Lisbon 3 M22:30 | 17/04/22 | R 30 Sporting Lisbon 0 Benfica Lisbon 2 G22:30 | 09/04/22 | R 29 CD Tondela 1 Sporting Lisbon 3 |
| 3 | |  Benfica Lisbon | 34 | 23 | 5 | 6 | 78 | 30 | 48 | 74 | G22:15 | 13/05/22 | R 34 FC Pacos Ferreira 0 Benfica Lisbon 2 M20:00 | 07/05/22 | R 33 Benfica Lisbon 0 FC Porto 1 G19:00 | 30/04/22 | R 32 Maritimo Madeira 0 Benfica Lisbon 1 B20:00 | 23/04/22 | R 31 Benfica Lisbon 0 FC Famalicao 0 G22:30 | 17/04/22 | R 30 Sporting Lisbon 0 Benfica Lisbon 2 G20:00 | 09/04/22 | R 29 Benfica Lisbon 3 B-SAD Lisbon 1 |
| 4 | |  SC Braga | 34 | 19 | 8 | 7 | 52 | 31 | 21 | 65 | M20:00 | 15/05/22 | R 34 FC Famalicao 3 SC Braga 2 G20:00 | 08/05/22 | R 33 SC Braga 1 FC Arouca 0 G23:00 | 30/04/22 | R 32 B-SAD Lisbon 0 SC Braga 1 G20:00 | 25/04/22 | R 31 SC Braga 1 FC Porto 0 B22:30 | 18/04/22 | R 30 Estoril Praia 0 SC Braga 0 G22:30 | 10/04/22 | R 29 FC Vizela 0 SC Braga 1 |
| 5 | |  Gil Vicente Barcelos | 34 | 13 | 12 | 9 | 47 | 42 | 5 | 51 | M22:30 | 15/05/22 | R 34 Vitoria Guimarares 5 Gil Vicente Barcelos 0 G17:30 | 08/05/22 | R 33 Gil Vicente Barcelos 3 CD Tondela 0 M22:30 | 01/05/22 | R 32 Sporting Lisbon 4 Gil Vicente Barcelos 1 B22:30 | 23/04/22 | R 31 Gil Vicente Barcelos 1 FC Pacos Ferreira 1 B20:00 | 15/04/22 | R 30 FC Famalicao 2 Gil Vicente Barcelos 2 M22:15 | 08/04/22 | R 29 Gil Vicente Barcelos 1 Moreirense FC 2 |
| 6 | |  Vitoria Guimarares | 34 | 13 | 9 | 12 | 50 | 41 | 9 | 48 | G22:30 | 15/05/22 | R 34 Vitoria Guimarares 5 Gil Vicente Barcelos 0 B22:15 | 06/05/22 | R 33 Boavista Porto 1 Vitoria Guimarares 1 B17:30 | 01/05/22 | R 32 Vitoria Guimarares 1 Santa Clara Azores 1 B22:30 | 24/04/22 | R 31 CD Tondela 1 Vitoria Guimarares 1 G22:30 | 15/04/22 | R 30 Vitoria Guimarares 4 FC Pacos Ferreira 0 M20:00 | 10/04/22 | R 29 Vitoria Guimarares 0 FC Porto 1 |
| 7 | |  Santa Clara Azores | 34 | 9 | 13 | 12 | 38 | 54 | -16 | 40 | M22:30 | 14/05/22 | R 34 Sporting Lisbon 4 Santa Clara Azores 0 G22:30 | 08/05/22 | R 33 Santa Clara Azores 2 FC Pacos Ferreira 0 B17:30 | 01/05/22 | R 32 Vitoria Guimarares 1 Santa Clara Azores 1 B20:00 | 23/04/22 | R 31 Santa Clara Azores 2 Maritimo Madeira 2 B17:30 | 15/04/22 | R 30 FC Arouca 1 Santa Clara Azores 1 G17:30 | 10/04/22 | R 29 Santa Clara Azores 2 Estoril Praia 0 |
| 8 | |  FC Famalicao | 34 | 9 | 12 | 13 | 45 | 51 | -6 | 39 | G20:00 | 15/05/22 | R 34 FC Famalicao 3 SC Braga 2 G22:15 | 09/05/22 | R 33 B-SAD Lisbon 2 FC Famalicao 3 G22:15 | 29/04/22 | R 32 FC Famalicao 3 Estoril Praia 1 B20:00 | 23/04/22 | R 31 Benfica Lisbon 0 FC Famalicao 0 B20:00 | 15/04/22 | R 30 FC Famalicao 2 Gil Vicente Barcelos 2 M17:30 | 10/04/22 | R 29 Portimonense SC 1 FC Famalicao 0 |
| 9 | |  Estoril Praia | 34 | 9 | 12 | 13 | 36 | 43 | -7 | 39 | M20:00 | 14/05/22 | R 34 FC Porto 2 Estoril Praia 0 G17:30 | 07/05/22 | R 33 Estoril Praia 1 Moreirense FC 0 M22:15 | 29/04/22 | R 32 FC Famalicao 3 Estoril Praia 1 B20:00 | 24/04/22 | R 31 Estoril Praia 2 B-SAD Lisbon 2 B22:30 | 18/04/22 | R 30 Estoril Praia 0 SC Braga 0 M17:30 | 10/04/22 | R 29 Santa Clara Azores 2 Estoril Praia 0 |
| 10 | |  Maritimo Madeira | 34 | 9 | 11 | 14 | 39 | 44 | -5 | 38 | M20:00 | 14/05/22 | R 34 Maritimo Madeira 0 Portimonense SC 1 B17:30 | 08/05/22 | R 33 FC Vizela 1 Maritimo Madeira 1 M19:00 | 30/04/22 | R 32 Maritimo Madeira 0 Benfica Lisbon 1 B20:00 | 23/04/22 | R 31 Santa Clara Azores 2 Maritimo Madeira 2 G20:00 | 16/04/22 | R 30 Maritimo Madeira 4 Boavista Porto 0 M17:30 | 09/04/22 | R 29 FC Pacos Ferreira 2 Maritimo Madeira 0 |
| 11 | |  FC Pacos Ferreira | 34 | 9 | 11 | 14 | 29 | 44 | -15 | 38 | M22:15 | 13/05/22 | R 34 FC Pacos Ferreira 0 Benfica Lisbon 2 M22:30 | 08/05/22 | R 33 Santa Clara Azores 2 FC Pacos Ferreira 0 B22:15 | 02/05/22 | R 32 FC Pacos Ferreira 1 CD Tondela 1 B22:30 | 23/04/22 | R 31 Gil Vicente Barcelos 1 FC Pacos Ferreira 1 M22:30 | 15/04/22 | R 30 Vitoria Guimarares 4 FC Pacos Ferreira 0 G17:30 | 09/04/22 | R 29 FC Pacos Ferreira 2 Maritimo Madeira 0 |
| 12 | |  Boavista Porto | 34 | 7 | 17 | 10 | 39 | 52 | -13 | 38 | B17:30 | 14/05/22 | R 34 CD Tondela 2 Boavista Porto 2 B22:15 | 06/05/22 | R 33 Boavista Porto 1 Vitoria Guimarares 1 G20:00 | 01/05/22 | R 32 Moreirense FC 1 Boavista Porto 2 M22:30 | 25/04/22 | R 31 Boavista Porto 0 Sporting Lisbon 3 M20:00 | 16/04/22 | R 30 Maritimo Madeira 4 Boavista Porto 0 G20:00 | 09/04/22 | R 29 Boavista Porto 1 FC Arouca 0 |
| 13 | |  Portimonense SC | 34 | 10 | 8 | 16 | 31 | 45 | -14 | 38 | G20:00 | 14/05/22 | R 34 Maritimo Madeira 0 Portimonense SC 1 M22:30 | 07/05/22 | R 33 Portimonense SC 2 Sporting Lisbon 3 M17:00 | 30/04/22 | R 32 FC Arouca 1 Portimonense SC 0 G17:30 | 23/04/22 | R 31 Portimonense SC 1 Moreirense FC 0 M22:30 | 16/04/22 | R 30 FC Porto 7 Portimonense SC 0 G17:30 | 10/04/22 | R 29 Portimonense SC 1 FC Famalicao 0 |
| 14 | |  FC Vizela | 34 | 7 | 12 | 15 | 37 | 58 | -21 | 33 | M17:30 | 14/05/22 | R 34 Moreirense FC 4 FC Vizela 1 B17:30 | 08/05/22 | R 33 FC Vizela 1 Maritimo Madeira 1 M21:00 | 30/04/22 | R 32 FC Porto 4 FC Vizela 2 G22:15 | 22/04/22 | R 31 FC Vizela 2 FC Arouca 1 M20:00 | 16/04/22 | R 30 B-SAD Lisbon 1 FC Vizela 0 M22:30 | 10/04/22 | R 29 FC Vizela 0 SC Braga 1 |
| 15 | |  FC Arouca | 34 | 7 | 10 | 17 | 30 | 54 | -24 | 31 | B17:30 | 14/05/22 | R 34 FC Arouca 0 B-SAD Lisbon 0 M20:00 | 08/05/22 | R 33 SC Braga 1 FC Arouca 0 G17:00 | 30/04/22 | R 32 FC Arouca 1 Portimonense SC 0 M22:15 | 22/04/22 | R 31 FC Vizela 2 FC Arouca 1 B17:30 | 15/04/22 | R 30 FC Arouca 1 Santa Clara Azores 1 M20:00 | 09/04/22 | R 29 Boavista Porto 1 FC Arouca 0 |
| 16 | |  Moreirense FC | 34 | 7 | 8 | 19 | 33 | 51 | -18 | 29 | G17:30 | 14/05/22 | R 34 Moreirense FC 4 FC Vizela 1 M17:30 | 07/05/22 | R 33 Estoril Praia 1 Moreirense FC 0 M20:00 | 01/05/22 | R 32 Moreirense FC 1 Boavista Porto 2 M17:30 | 23/04/22 | R 31 Portimonense SC 1 Moreirense FC 0 |
| 17 | |  CD Tondela | 34 | 7 | 7 | 20 | 41 | 67 | -26 | 28 | B17:30 | 14/05/22 | R 34 CD Tondela 2 Boavista Porto 2 M17:30 | 08/05/22 | R 33 Gil Vicente Barcelos 3 CD Tondela 0 B22:15 | 02/05/22 | R 32 FC Pacos Ferreira 1 CD Tondela 1 B22:30 | 24/04/22 | R 31 CD Tondela 1 Vitoria Guimarares 1 M17:30 | 16/04/22 | R 30 Moreirense FC 2 CD Tondela 0 M22:30 | 09/04/22 | R 29 CD Tondela 1 Sporting Lisbon 3 |
| 18 | |  B-SAD Lisbon | 34 | 5 | 11 | 18 | 23 | 55 | -32 | 26 | B17:30 | 14/05/22 | R 34 FC Arouca 0 B-SAD Lisbon 0 M22:15 | 09/05/22 | R 33 B-SAD Lisbon 2 FC Famalicao 3 M23:00 | 30/04/22 | R 32 B-SAD Lisbon 0 SC Braga 1 B20:00 | 24/04/22 | R 31 Estoril Praia 2 B-SAD Lisbon 2 G20:00 | 16/04/22 | R 30 B-SAD Lisbon 1 FC Vizela 0 M20:00 | 09/04/22 | R 29 Benfica Lisbon 3 B-SAD Lisbon 1 |
