| 1 | |  Asante Kotoko | 34 | 19 | 10 | 5 | 48 | 20 | 28 | 67 | B18:00 | 18/06/22 | R 34  Accra Lions 1 Asante Kotoko 1 G21:00 | 12/06/22 | R 33 Asante Kotoko 3 Elmina Sharks 0 G18:00 | 05/06/22 | R 32 Accra Great Olympics 0 Asante Kotoko 1 B18:00 | 02/06/22 | R 29 Ashanti Gold FC 1 Asante Kotoko 1 G18:00 | 29/05/22 | R 31 Medeama SC 0 Asante Kotoko 2 M18:00 | 22/05/22 | R 30 Asante Kotoko 0 Berekum Chelsea Fc 1 |
| 2 | |  Medeama SC | 34 | 16 | 8 | 10 | 28 | 25 | 3 | 56 | M18:00 | 19/06/22 | R 34 Dreams FC 2 Medeama SC 0 G18:00 | 12/06/22 | R 33 Medeama SC 2 Accra Lions 1 G18:00 | 05/06/22 | R 32 Elmina Sharks 1 Medeama SC 3 M18:00 | 29/05/22 | R 31 Medeama SC 0 Asante Kotoko 2 G18:00 | 21/05/22 | R 30 Accra Great Olympics 1 Medeama SC 2 B18:00 | 18/05/22 | R 29 Berekum Chelsea Fc 0 Medeama SC 0 |
| 3 | |  Bechem United | 34 | 13 | 15 | 6 | 37 | 24 | 13 | 54 | B18:00 | 19/06/22 | R 34 Bechem United 1 Berekum Chelsea Fc 1 M18:00 | 12/06/22 | R 33 Ashanti Gold FC 2 Bechem United 1 G18:00 | 05/06/22 | R 32 Bechem United 1 Aduana Stars 0 B18:00 | 29/05/22 | R 31 Sogakope Wafa 1 Bechem United 1 B18:00 | 22/05/22 | R 30 Bechem United 0 Legon Cities FC 0 B18:00 | 18/05/22 | R 29 Real Tamale United 2 Bechem United 2 |
| 4 | |  Karela United Fc | 34 | 13 | 13 | 8 | 43 | 33 | 10 | 52 | G18:00 | 19/06/22 | R 34 Karela United Fc 1 Sogakope Wafa 0 B18:00 | 12/06/22 | R 33 Legon Cities FC 0 Karela United Fc 0 G18:00 | 05/06/22 | R 32 Karela United Fc 5 Real Tamale United 1 B18:00 | 30/05/22 | R 31 Hearts of Oak 1 Karela United Fc 1 B18:00 | 22/05/22 | R 30 Karela United Fc 1 King Faisal 1 G18:00 | 18/05/22 | R 29 Karela United Fc 1 Accra Great Olympics 0 |
| 5 | |  Accra Great Olympics | 34 | 12 | 12 | 10 | 36 | 31 | 5 | 48 | B18:00 | 19/06/22 | R 34 Elmina Sharks 2 Accra Great Olympics 2 G18:00 | 12/06/22 | R 33 Accra Great Olympics 3 Hearts of Oak 0 M18:00 | 05/06/22 | R 32 Accra Great Olympics 0 Asante Kotoko 1 B18:00 | 29/05/22 | R 31 King Faisal 1 Accra Great Olympics 1 M18:00 | 21/05/22 | R 30 Accra Great Olympics 1 Medeama SC 2 M18:00 | 18/05/22 | R 29 Karela United Fc 1 Accra Great Olympics 0 |
| 6 | |  Hearts of Oak | 34 | 12 | 12 | 10 | 33 | 29 | 4 | 48 | M18:00 | 19/06/22 | R 34 Hearts of Oak 1 Real Tamale United 4 M18:00 | 12/06/22 | R 33 Accra Great Olympics 3 Hearts of Oak 0 M18:00 | 08/06/22 | R 30 Eleven Wonders FC 2 Hearts of Oak 1 M21:00 | 05/06/22 | R 32 King Faisal 1 Hearts of Oak 0 B18:00 | 30/05/22 | R 31 Hearts of Oak 1 Karela United Fc 1 G18:00 | 18/05/22 | R 29 Hearts of Oak 1 Bibiani Gold Stars FC 0 |
| 7 | |  Ashanti Gold FC | 34 | 13 | 8 | 13 | 46 | 37 | 9 | 47 | B18:00 | 19/06/22 | R 34 Bibiani Gold Stars FC 2 Ashanti Gold FC 2 G18:00 | 12/06/22 | R 33 Ashanti Gold FC 2 Bechem United 1 M18:00 | 05/06/22 | R 32 Dreams FC 1 Ashanti Gold FC 0 B18:00 | 02/06/22 | R 29 Ashanti Gold FC 1 Asante Kotoko 1 B18:00 | 29/05/22 | R 31 Ashanti Gold FC 2 Accra Lions 2 G18:00 | 22/05/22 | R 30 Elmina Sharks 1 Ashanti Gold FC 3 |
| 8 | |  Berekum Chelsea Fc | 34 | 12 | 11 | 11 | 29 | 30 | -1 | 47 | B18:00 | 19/06/22 | R 34 Bechem United 1 Berekum Chelsea Fc 1 M18:00 | 12/06/22 | R 33 Berekum Chelsea Fc 0 Dreams FC 1 M18:00 | 04/06/22 | R 32 Accra Lions 2 Berekum Chelsea Fc 0 G18:00 | 29/05/22 | R 31 Berekum Chelsea Fc 3 Elmina Sharks 0 G18:00 | 22/05/22 | R 30 Asante Kotoko 0 Berekum Chelsea Fc 1 B18:00 | 18/05/22 | R 29 Berekum Chelsea Fc 0 Medeama SC 0 |
| 9 | |  Legon Cities FC | 34 | 11 | 13 | 10 | 34 | 26 | 8 | 46 | M18:00 | 19/06/22 | R 34 King Faisal 2 Legon Cities FC 1 B18:00 | 12/06/22 | R 33 Legon Cities FC 0 Karela United Fc 0 B18:00 | 05/06/22 | R 32 Eleven Wonders FC 0 Legon Cities FC 0 B18:00 | 29/05/22 | R 31 Legon Cities FC 1 Bibiani Gold Stars FC 1 B18:00 | 22/05/22 | R 30 Bechem United 0 Legon Cities FC 0 G18:00 | 18/05/22 | R 29 Legon Cities FC 2 Dreams FC 1 |
| 10 | |  Bibiani Gold Stars FC | 34 | 14 | 4 | 16 | 34 | 40 | -6 | 46 | B18:00 | 19/06/22 | R 34 Bibiani Gold Stars FC 2 Ashanti Gold FC 2 G18:00 | 12/06/22 | R 33 Aduana Stars 0 Bibiani Gold Stars FC 1 M18:00 | 05/06/22 | R 32 Bibiani Gold Stars FC 3 Sogakope Wafa 4 B18:00 | 29/05/22 | R 31 Legon Cities FC 1 Bibiani Gold Stars FC 1 G18:00 | 22/05/22 | R 30 Bibiani Gold Stars FC 2 Real Tamale United 0 M18:00 | 18/05/22 | R 29 Hearts of Oak 1 Bibiani Gold Stars FC 0 |
| 11 | |  Aduana Stars | 34 | 11 | 12 | 11 | 33 | 28 | 5 | 45 | M18:00 | 19/06/22 | R 34 Eleven Wonders FC 2 Aduana Stars 1 M18:00 | 12/06/22 | R 33 Aduana Stars 0 Bibiani Gold Stars FC 1 M18:00 | 05/06/22 | R 32 Bechem United 1 Aduana Stars 0 B18:00 | 29/05/22 | R 31 Aduana Stars 0 Dreams FC 0 B18:00 | 22/05/22 | R 30 Accra Lions 0 Aduana Stars 0 B18:00 | 18/05/22 | R 29 Aduana Stars 0 Elmina Sharks 0 |
| 12 | |  Accra Lions | 34 | 12 | 9 | 13 | 26 | 38 | -12 | 45 | B18:00 | 18/06/22 | R 34 Accra Lions 1 Asante Kotoko 1 M18:00 | 12/06/22 | R 33 Medeama SC 2 Accra Lions 1 G18:00 | 04/06/22 | R 32 Accra Lions 2 Berekum Chelsea Fc 0 B18:00 | 29/05/22 | R 31 Ashanti Gold FC 2 Accra Lions 2 B18:00 | 22/05/22 | R 30 Accra Lions 0 Aduana Stars 0 G18:00 | 18/05/22 | R 29 Sogakope Wafa 0 Accra Lions 1 |
| 13 | |  Dreams FC | 34 | 11 | 11 | 12 | 47 | 44 | 3 | 44 | G18:00 | 19/06/22 | R 34 Dreams FC 2 Medeama SC 0 G18:00 | 12/06/22 | R 33 Berekum Chelsea Fc 0 Dreams FC 1 G18:00 | 05/06/22 | R 32 Dreams FC 1 Ashanti Gold FC 0 B18:00 | 29/05/22 | R 31 Aduana Stars 0 Dreams FC 0 B18:00 | 22/05/22 | R 30 Dreams FC 1 Sogakope Wafa 1 M18:00 | 18/05/22 | R 29 Legon Cities FC 2 Dreams FC 1 |
| 14 | |  King Faisal | 34 | 12 | 6 | 16 | 30 | 34 | -4 | 42 | G18:00 | 19/06/22 | R 34 King Faisal 2 Legon Cities FC 1 M18:00 | 12/06/22 | R 33 Real Tamale United 1 King Faisal 0 G21:00 | 05/06/22 | R 32 King Faisal 1 Hearts of Oak 0 B18:00 | 29/05/22 | R 31 King Faisal 1 Accra Great Olympics 1 B18:00 | 22/05/22 | R 30 Karela United Fc 1 King Faisal 1 G18:00 | 18/05/22 | R 29 King Faisal 1 Eleven Wonders FC 0 |
| 15 | |  Real Tamale United | 34 | 10 | 11 | 13 | 40 | 48 | -8 | 41 | G18:00 | 19/06/22 | R 34 Hearts of Oak 1 Real Tamale United 4 G18:00 | 12/06/22 | R 33 Real Tamale United 1 King Faisal 0 M18:00 | 05/06/22 | R 32 Karela United Fc 5 Real Tamale United 1 B18:00 | 29/05/22 | R 31 Real Tamale United 0 Eleven Wonders FC 0 M18:00 | 22/05/22 | R 30 Bibiani Gold Stars FC 2 Real Tamale United 0 B18:00 | 18/05/22 | R 29 Real Tamale United 2 Bechem United 2 |
| 16 | |  Eleven Wonders FC | 34 | 10 | 10 | 14 | 29 | 38 | -9 | 40 | G18:00 | 19/06/22 | R 34 Eleven Wonders FC 2 Aduana Stars 1 M18:00 | 12/06/22 | R 33 Sogakope Wafa 1 Eleven Wonders FC 0 G18:00 | 08/06/22 | R 30 Eleven Wonders FC 2 Hearts of Oak 1 B18:00 | 05/06/22 | R 32 Eleven Wonders FC 0 Legon Cities FC 0 B18:00 | 29/05/22 | R 31 Real Tamale United 0 Eleven Wonders FC 0 M18:00 | 18/05/22 | R 29 King Faisal 1 Eleven Wonders FC 0 |
| 17 | |  Sogakope Wafa | 34 | 8 | 11 | 15 | 27 | 42 | -15 | 35 | M18:00 | 19/06/22 | R 34 Karela United Fc 1 Sogakope Wafa 0 G18:00 | 12/06/22 | R 33 Sogakope Wafa 1 Eleven Wonders FC 0 G18:00 | 05/06/22 | R 32 Bibiani Gold Stars FC 3 Sogakope Wafa 4 B18:00 | 29/05/22 | R 31 Sogakope Wafa 1 Bechem United 1 B18:00 | 22/05/22 | R 30 Dreams FC 1 Sogakope Wafa 1 M18:00 | 18/05/22 | R 29 Sogakope Wafa 0 Accra Lions 1 |
| 18 | |  Elmina Sharks | 34 | 5 | 8 | 21 | 24 | 57 | -33 | 23 | B18:00 | 19/06/22 | R 34 Elmina Sharks 2 Accra Great Olympics 2 M21:00 | 12/06/22 | R 33 Asante Kotoko 3 Elmina Sharks 0 M18:00 | 05/06/22 | R 32 Elmina Sharks 1 Medeama SC 3 M18:00 | 29/05/22 | R 31 Berekum Chelsea Fc 3 Elmina Sharks 0 M18:00 | 22/05/22 | R 30 Elmina Sharks 1 Ashanti Gold FC 3 B18:00 | 18/05/22 | R 29 Aduana Stars 0 Elmina Sharks 0 |
