| 1 | |  CA River Plate (Arg) | 25 | 16 | 6 | 3 | 53 | 19 | 34 | 54 | B01:15 | 12/12/21 | R 25  Atletico Tucuman 1 CA River Plate (Arg) 1 M03:30 | 06/12/21 | R 24 CA River Plate (Arg) 2 Defensa Y Justicia 3 B23:00 | 28/11/21 | R 23 CA Rosario Central 2 CA River Plate (Arg) 2 G03:30 | 26/11/21 | R 22 CA River Plate (Arg) 4 Racing Club Avellaneda 0 G03:30 | 22/11/21 | R 21 CA Platense 0 CA River Plate (Arg) 1 G02:15 | 08/11/21 | R 20 CA River Plate (Arg) 5 CA Patronato Parana 0 |
| 2 | |  Defensa Y Justicia | 25 | 13 | 8 | 4 | 43 | 24 | 19 | 47 | G01:15 | 13/12/21 | R 25 Defensa Y Justicia 2 Atletico Lanus 1 G03:30 | 06/12/21 | R 24 CA River Plate (Arg) 2 Defensa Y Justicia 3 B01:15 | 29/11/21 | R 23 Defensa Y Justicia 1 Colon de Santa Fe 1 G01:15 | 25/11/21 | R 22 Atletico Tucuman 0 Defensa Y Justicia 4 G23:00 | 18/11/21 | R 21 Union de Santa Fe 2 Defensa Y Justicia 3 G01:00 | 06/11/21 | R 20 Defensa Y Justicia 3 CA Rosario Central 0 |
| 3 | |  CA Talleres de Cordoba | 25 | 14 | 4 | 7 | 38 | 28 | 10 | 46 | M03:30 | 13/12/21 | R 25 CA Talleres de Cordoba 1 CA Independiente Avellaneda 2 G01:15 | 05/12/21 | R 24 CA Sarmiento Junin 1 CA Talleres de Cordoba 2 G23:00 | 27/11/21 | R 23 CA Talleres de Cordoba 2 CA Aldosivi 0 M23:00 | 23/11/21 | R 22 Gimnasia Y Esgrima La Plata 5 CA Talleres de Cordoba 2 B03:30 | 20/11/21 | R 21 CA Talleres de Cordoba 1 Velez Sarsfield 1 G21:45 | 06/11/21 | R 20 CD Godoy Cruz 0 CA Talleres de Cordoba 2 |
| 4 | |  Boca Juniors | 25 | 11 | 8 | 6 | 35 | 19 | 16 | 41 | G04:00 | 12/12/21 | R 25 Boca Juniors 8 CA Central Cordoba SE 1 B23:00 | 04/12/21 | R 24 Arsenal de Sarandi 1 Boca Juniors 1 B01:15 | 01/12/21 | R 23 Boca Juniors 0 Newells Old Boys 0 M03:30 | 25/11/21 | R 22 CA Independiente Avellaneda 1 Boca Juniors 0 G01:15 | 21/11/21 | R 21 Boca Juniors 2 CA Sarmiento Junin 0 G03:15 | 09/11/21 | R 20 CA Aldosivi 0 Boca Juniors 3 |
| 5 | |  Velez Sarsfield | 25 | 10 | 9 | 6 | 34 | 21 | 13 | 39 | M01:15 | 11/12/21 | R 25 CA Platense 3 Velez Sarsfield 2 B03:30 | 04/12/21 | R 24 Velez Sarsfield 0 CA Patronato Parana 0 M03:30 | 28/11/21 | R 23 Estudiantes de La Plata 1 Velez Sarsfield 0 G03:30 | 24/11/21 | R 22 Velez Sarsfield 2 Argentinos Juniors 0 B03:30 | 20/11/21 | R 21 CA Talleres de Cordoba 1 Velez Sarsfield 1 G00:00 | 08/11/21 | R 20 Velez Sarsfield 2 CA San Lorenzo Almagro 1 |
| 6 | |  Estudiantes de La Plata | 25 | 10 | 9 | 6 | 43 | 31 | 12 | 39 | M03:30 | 11/12/21 | R 25 Estudiantes de La Plata 2 CA Aldosivi 3 B23:00 | 05/12/21 | R 24 Gimnasia Y Esgrima La Plata 4 Estudiantes de La Plata 4 G03:30 | 28/11/21 | R 23 Estudiantes de La Plata 1 Velez Sarsfield 0 G03:30 | 24/11/21 | R 22 CD Godoy Cruz 1 Estudiantes de La Plata 3 G23:00 | 19/11/21 | R 21 Estudiantes de La Plata 4 CA Huracan 1 B03:15 | 06/11/21 | R 20 Atletico Lanus 1 Estudiantes de La Plata 1 |
| 7 | |  Colon de Santa Fe | 25 | 11 | 6 | 8 | 26 | 31 | -5 | 39 | M23:00 | 11/12/21 | R 25 Union de Santa Fe 3 Colon de Santa Fe 0 G01:15 | 04/12/21 | R 24 Colon de Santa Fe 3 Atletico Tucuman 0 B01:15 | 29/11/21 | R 23 Defensa Y Justicia 1 Colon de Santa Fe 1 M01:15 | 26/11/21 | R 22 Colon de Santa Fe 1 CA Rosario Central 4 G01:15 | 22/11/21 | R 21 Racing Club Avellaneda 1 Colon de Santa Fe 2 G21:45 | 06/11/21 | R 20 Colon de Santa Fe 3 CA Platense 0 |
| 8 | |  CA Huracan | 25 | 10 | 8 | 7 | 28 | 25 | 3 | 38 | G23:00 | 11/12/21 | R 25 CA Rosario Central 1 CA Huracan 4 G03:30 | 05/12/21 | R 24 CA Huracan 1 Racing Club Avellaneda 0 M03:30 | 30/11/21 | R 23 CA Platense 4 CA Huracan 2 G23:00 | 23/11/21 | R 22 CA Huracan 1 CA Patronato Parana 0 M23:00 | 19/11/21 | R 21 Estudiantes de La Plata 4 CA Huracan 1 B01:00 | 09/11/21 | R 20 CA Huracan 1 Argentinos Juniors 1 |
| 9 | |  CA Independiente Avellaneda | 25 | 10 | 8 | 7 | 27 | 24 | 3 | 38 | G03:30 | 13/12/21 | R 25 CA Talleres de Cordoba 1 CA Independiente Avellaneda 2 B01:15 | 06/12/21 | R 24 CA Independiente Avellaneda 1 CA San Lorenzo Almagro 1 M03:30 | 01/12/21 | R 23 CA Banfield 4 CA Independiente Avellaneda 1 G03:30 | 25/11/21 | R 22 CA Independiente Avellaneda 1 Boca Juniors 0 M03:30 | 21/11/21 | R 21 CA Central Cordoba SE 1 CA Independiente Avellaneda 0 G00:00 | 07/11/21 | R 20 CA Independiente Avellaneda 3 Arsenal de Sarandi 0 |
| 10 | |  Atletico Lanus | 25 | 10 | 7 | 8 | 44 | 43 | 1 | 37 | M01:15 | 13/12/21 | R 25 Defensa Y Justicia 2 Atletico Lanus 1 B03:30 | 05/12/21 | R 24 Atletico Lanus 2 CA Rosario Central 2 M01:15 | 30/11/21 | R 23 Racing Club Avellaneda 3 Atletico Lanus 1 B01:15 | 26/11/21 | R 22 Atletico Lanus 3 CA Platense 3 M01:15 | 19/11/21 | R 21 CA Patronato Parana 3 Atletico Lanus 2 B03:15 | 06/11/21 | R 20 Atletico Lanus 1 Estudiantes de La Plata 1 |
| 11 | |  Gimnasia Y Esgrima La Plata | 25 | 9 | 9 | 7 | 27 | 28 | -1 | 36 | B23:00 | 11/12/21 | R 25 CA Patronato Parana 0 Gimnasia Y Esgrima La Plata 0 B23:00 | 05/12/21 | R 24 Gimnasia Y Esgrima La Plata 4 Estudiantes de La Plata 4 M01:15 | 29/11/21 | R 23 Argentinos Juniors 3 Gimnasia Y Esgrima La Plata 0 G23:00 | 23/11/21 | R 22 Gimnasia Y Esgrima La Plata 5 CA Talleres de Cordoba 2 G01:15 | 20/11/21 | R 21 CA San Lorenzo Almagro 0 Gimnasia Y Esgrima La Plata 1 M21:45 | 07/11/21 | R 20 Gimnasia Y Esgrima La Plata 0 CA Banfield 1 |
| 12 | |  Union de Santa Fe | 25 | 10 | 4 | 11 | 32 | 32 | 0 | 34 | G23:00 | 11/12/21 | R 25 Union de Santa Fe 3 Colon de Santa Fe 0 M01:15 | 04/12/21 | R 24 CA Central Cordoba SE 2 Union de Santa Fe 0 G23:00 | 29/11/21 | R 23 Union de Santa Fe 3 Atletico Tucuman 0 G23:00 | 25/11/21 | R 22 Arsenal de Sarandi 0 Union de Santa Fe 1 M23:00 | 18/11/21 | R 21 Union de Santa Fe 2 Defensa Y Justicia 3 M22:45 | 08/11/21 | R 20 Newells Old Boys 1 Union de Santa Fe 0 |
| 13 | |  CA Aldosivi | 25 | 10 | 3 | 12 | 29 | 39 | -10 | 33 | G03:30 | 11/12/21 | R 25 Estudiantes de La Plata 2 CA Aldosivi 3 G01:15 | 07/12/21 | R 24 CA Aldosivi 3 Argentinos Juniors 2 M23:00 | 27/11/21 | R 23 CA Talleres de Cordoba 2 CA Aldosivi 0 G01:15 | 24/11/21 | R 22 CA Aldosivi 2 CA San Lorenzo Almagro 0 G03:30 | 19/11/21 | R 21 CA Banfield 0 CA Aldosivi 2 M03:15 | 09/11/21 | R 20 CA Aldosivi 0 Boca Juniors 3 |
| 14 | |  Argentinos Juniors | 25 | 8 | 8 | 9 | 26 | 25 | 1 | 32 | G23:00 | 11/12/21 | R 25 Argentinos Juniors 2 CA Sarmiento Junin 0 M01:15 | 07/12/21 | R 24 CA Aldosivi 3 Argentinos Juniors 2 G01:15 | 29/11/21 | R 23 Argentinos Juniors 3 Gimnasia Y Esgrima La Plata 0 M03:30 | 24/11/21 | R 22 Velez Sarsfield 2 Argentinos Juniors 0 B03:30 | 20/11/21 | R 21 Argentinos Juniors 0 CD Godoy Cruz 0 B01:00 | 09/11/21 | R 20 CA Huracan 1 Argentinos Juniors 1 |
| 15 | |  Racing Club Avellaneda | 25 | 8 | 8 | 9 | 24 | 23 | 1 | 32 | G23:00 | 11/12/21 | R 25 Racing Club Avellaneda 2 CD Godoy Cruz 1 M03:30 | 05/12/21 | R 24 CA Huracan 1 Racing Club Avellaneda 0 G01:15 | 30/11/21 | R 23 Racing Club Avellaneda 3 Atletico Lanus 1 M03:30 | 26/11/21 | R 22 CA River Plate (Arg) 4 Racing Club Avellaneda 0 M01:15 | 22/11/21 | R 21 Racing Club Avellaneda 1 Colon de Santa Fe 2 G02:15 | 07/11/21 | R 20 Atletico Tucuman 0 Racing Club Avellaneda 2 |
| 16 | |  CA Rosario Central | 25 | 9 | 5 | 11 | 39 | 41 | -2 | 32 | M23:00 | 11/12/21 | R 25 CA Rosario Central 1 CA Huracan 4 B03:30 | 05/12/21 | R 24 Atletico Lanus 2 CA Rosario Central 2 B23:00 | 28/11/21 | R 23 CA Rosario Central 2 CA River Plate (Arg) 2 G01:15 | 26/11/21 | R 22 Colon de Santa Fe 1 CA Rosario Central 4 G23:00 | 20/11/21 | R 21 CA Rosario Central 3 Atletico Tucuman 1 M01:00 | 06/11/21 | R 20 Defensa Y Justicia 3 CA Rosario Central 0 |
| 17 | |  CD Godoy Cruz | 25 | 8 | 7 | 10 | 35 | 33 | 2 | 31 | M23:00 | 11/12/21 | R 25 Racing Club Avellaneda 2 CD Godoy Cruz 1 B01:15 | 05/12/21 | R 24 CD Godoy Cruz 2 CA Platense 2 G01:15 | 28/11/21 | R 23 CA Patronato Parana 0 CD Godoy Cruz 3 M03:30 | 24/11/21 | R 22 CD Godoy Cruz 1 Estudiantes de La Plata 3 B03:30 | 20/11/21 | R 21 Argentinos Juniors 0 CD Godoy Cruz 0 M21:45 | 06/11/21 | R 20 CD Godoy Cruz 0 CA Talleres de Cordoba 2 |
| 18 | |  CA Platense | 25 | 7 | 10 | 8 | 36 | 36 | 0 | 31 | G01:15 | 11/12/21 | R 25 CA Platense 3 Velez Sarsfield 2 B01:15 | 05/12/21 | R 24 CD Godoy Cruz 2 CA Platense 2 G03:30 | 30/11/21 | R 23 CA Platense 4 CA Huracan 2 B01:15 | 26/11/21 | R 22 Atletico Lanus 3 CA Platense 3 M03:30 | 22/11/21 | R 21 CA Platense 0 CA River Plate (Arg) 1 M21:45 | 06/11/21 | R 20 Colon de Santa Fe 3 CA Platense 0 |
| 19 | |  Newells Old Boys | 25 | 7 | 7 | 11 | 24 | 32 | -8 | 28 | M23:00 | 12/12/21 | R 25 CA San Lorenzo Almagro 3 Newells Old Boys 2 B03:30 | 07/12/21 | R 24 Newells Old Boys 0 CA Banfield 0 B01:15 | 01/12/21 | R 23 Boca Juniors 0 Newells Old Boys 0 G23:00 | 24/11/21 | R 22 Newells Old Boys 1 CA Central Cordoba SE 0 M23:00 | 21/11/21 | R 21 Arsenal de Sarandi 3 Newells Old Boys 1 G22:45 | 08/11/21 | R 20 Newells Old Boys 1 Union de Santa Fe 0 |
| 20 | |  CA Banfield | 25 | 5 | 12 | 8 | 20 | 25 | -5 | 27 | B02:00 | 14/12/21 | R 25 CA Banfield 0 Arsenal de Sarandi 0 B03:30 | 07/12/21 | R 24 Newells Old Boys 0 CA Banfield 0 G03:30 | 01/12/21 | R 23 CA Banfield 4 CA Independiente Avellaneda 1 B23:00 | 24/11/21 | R 22 CA Sarmiento Junin 0 CA Banfield 0 M03:30 | 19/11/21 | R 21 CA Banfield 0 CA Aldosivi 2 G21:45 | 07/11/21 | R 20 Gimnasia Y Esgrima La Plata 0 CA Banfield 1 |
| 21 | |  CA San Lorenzo Almagro | 25 | 7 | 6 | 12 | 23 | 33 | -10 | 27 | G23:00 | 12/12/21 | R 25 CA San Lorenzo Almagro 3 Newells Old Boys 2 B01:15 | 06/12/21 | R 24 CA Independiente Avellaneda 1 CA San Lorenzo Almagro 1 G23:00 | 30/11/21 | R 23 CA San Lorenzo Almagro 1 CA Sarmiento Junin 0 M01:15 | 24/11/21 | R 22 CA Aldosivi 2 CA San Lorenzo Almagro 0 M01:15 | 20/11/21 | R 21 CA San Lorenzo Almagro 0 Gimnasia Y Esgrima La Plata 1 M00:00 | 08/11/21 | R 20 Velez Sarsfield 2 CA San Lorenzo Almagro 1 |
| 22 | |  CA Central Cordoba SE | 25 | 6 | 8 | 11 | 30 | 36 | -6 | 26 | M04:00 | 12/12/21 | R 25 Boca Juniors 8 CA Central Cordoba SE 1 G01:15 | 04/12/21 | R 24 CA Central Cordoba SE 2 Union de Santa Fe 0 G03:30 | 30/11/21 | R 23 CA Central Cordoba SE 5 Arsenal de Sarandi 0 M23:00 | 24/11/21 | R 22 Newells Old Boys 1 CA Central Cordoba SE 0 G03:30 | 21/11/21 | R 21 CA Central Cordoba SE 1 CA Independiente Avellaneda 0 G21:45 | 07/11/21 | R 20 CA Sarmiento Junin 1 CA Central Cordoba SE 3 |
| 23 | |  CA Patronato Parana | 25 | 5 | 10 | 10 | 23 | 35 | -12 | 25 | B23:00 | 11/12/21 | R 25 CA Patronato Parana 0 Gimnasia Y Esgrima La Plata 0 B03:30 | 04/12/21 | R 24 Velez Sarsfield 0 CA Patronato Parana 0 M01:15 | 28/11/21 | R 23 CA Patronato Parana 0 CD Godoy Cruz 3 M23:00 | 23/11/21 | R 22 CA Huracan 1 CA Patronato Parana 0 G01:15 | 19/11/21 | R 21 CA Patronato Parana 3 Atletico Lanus 2 M02:15 | 08/11/21 | R 20 CA River Plate (Arg) 5 CA Patronato Parana 0 |
| 24 | |  CA Sarmiento Junin | 25 | 6 | 6 | 13 | 23 | 33 | -10 | 24 | M23:00 | 11/12/21 | R 25 Argentinos Juniors 2 CA Sarmiento Junin 0 M01:15 | 05/12/21 | R 24 CA Sarmiento Junin 1 CA Talleres de Cordoba 2 M23:00 | 30/11/21 | R 23 CA San Lorenzo Almagro 1 CA Sarmiento Junin 0 B23:00 | 24/11/21 | R 22 CA Sarmiento Junin 0 CA Banfield 0 M01:15 | 21/11/21 | R 21 Boca Juniors 2 CA Sarmiento Junin 0 M21:45 | 07/11/21 | R 20 CA Sarmiento Junin 1 CA Central Cordoba SE 3 |
| 25 | |  Atletico Tucuman | 25 | 5 | 7 | 13 | 22 | 46 | -24 | 22 | B01:15 | 12/12/21 | R 25 Atletico Tucuman 1 CA River Plate (Arg) 1 M01:15 | 04/12/21 | R 24 Colon de Santa Fe 3 Atletico Tucuman 0 M23:00 | 29/11/21 | R 23 Union de Santa Fe 3 Atletico Tucuman 0 M01:15 | 25/11/21 | R 22 Atletico Tucuman 0 Defensa Y Justicia 4 M23:00 | 20/11/21 | R 21 CA Rosario Central 3 Atletico Tucuman 1 M02:15 | 07/11/21 | R 20 Atletico Tucuman 0 Racing Club Avellaneda 2 |
| 26 | |  Arsenal de Sarandi | 25 | 4 | 9 | 12 | 12 | 34 | -22 | 21 | B02:00 | 14/12/21 | R 25 CA Banfield 0 Arsenal de Sarandi 0 B23:00 | 04/12/21 | R 24 Arsenal de Sarandi 1 Boca Juniors 1 M03:30 | 30/11/21 | R 23 CA Central Cordoba SE 5 Arsenal de Sarandi 0 M23:00 | 25/11/21 | R 22 Arsenal de Sarandi 0 Union de Santa Fe 1 G23:00 | 21/11/21 | R 21 Arsenal de Sarandi 3 Newells Old Boys 1 M00:00 | 07/11/21 | R 20 CA Independiente Avellaneda 3 Arsenal de Sarandi 0 |
