| 1 | |  CF Tigres UANL | 17 | 15 | 1 | 1 | 50 | 11 | 39 | 46 | |
| 2 | |  Atlas FC | 17 | 13 | 2 | 2 | 45 | 18 | 27 | 41 | G19:00 | 19/11/20 | R 17  Atlas FC 3 CF Monterrey 1 G02:00 | 17/11/20 | R 16 CF Pachuca 1 Atlas FC 3 G19:00 | 09/11/20 | R 15 Atlas FC 2 Pumas Unam 1 M04:00 | 06/11/20 | R 14 CF Tigres UANL 3 Atlas FC 0 |
| 3 | |  CF Monterrey | 17 | 13 | 2 | 2 | 41 | 19 | 22 | 41 | |
| 4 | |  CD Guadalajara | 17 | 12 | 2 | 3 | 42 | 17 | 25 | 38 | M03:00 | 21/11/20 | R 17 CF Tigres UANL 4 CD Guadalajara 1 M04:00 | 17/11/20 | R 16 CD Guadalajara 1 Club America 2 G21:00 | 08/11/20 | R 15 Puebla FC 0 CD Guadalajara 5 G19:30 | 05/11/20 | R 14 CD Guadalajara 3 Club Tijuana de Caliente 0 |
| 5 | |  Club America | 17 | 11 | 4 | 2 | 35 | 12 | 23 | 37 | G21:00 | 20/11/20 | R 17 Club America 3 CF Pachuca 0 G04:00 | 17/11/20 | R 16 CD Guadalajara 1 Club America 2 |
| 6 | |  Pumas Unam | 17 | 8 | 3 | 6 | 25 | 15 | 10 | 27 | M02:00 | 20/11/20 | R 17 Club Leon 3 Pumas Unam 2 G20:00 | 14/11/20 | R 16 Pumas Unam 1 Mazatlan FC 0 M19:00 | 09/11/20 | R 15 Atlas FC 2 Pumas Unam 1 G21:00 | 05/11/20 | R 14 Pumas Unam 4 Club Necaxa 0 |
| 7 | |  Queretaro FC | 17 | 7 | 5 | 5 | 24 | 20 | 4 | 26 | M01:00 | 21/11/20 | R 17 Queretaro FC 1 Cruz Azul 2 B02:00 | 14/11/20 | R 16 Queretaro FC 1 Puebla FC 1 |
| 8 | |  CF Pachuca | 17 | 7 | 3 | 7 | 24 | 25 | -1 | 24 | M21:00 | 20/11/20 | R 17 Club America 3 CF Pachuca 0 M02:00 | 17/11/20 | R 16 CF Pachuca 1 Atlas FC 3 B04:00 | 10/11/20 | R 15 CF Monterrey 2 CF Pachuca 2 B04:00 | 06/11/20 | R 14 CF Pachuca 2 FC Juarez 2 |
| 9 | |  Club Santos Laguna | 17 | 5 | 6 | 6 | 17 | 20 | -3 | 21 | G04:00 | 20/11/20 | R 17 Club Santos Laguna 2 Deportivo Toluca FC 0 B18:00 | 14/11/20 | R 16 Cruz Azul 0 Club Santos Laguna 0 G04:00 | 10/11/20 | R 15 Club Santos Laguna 2 Atletico San Luis 1 B06:00 | 06/11/20 | R 14 Club Santos Laguna 1 Mazatlan FC 1 G01:00 | 02/11/20 | R 13 Club Necaxa 2 Club Santos Laguna 4 M20:00 | 19/10/20 | R 12 Queretaro FC 2 Club Santos Laguna 1 |
| 10 | |  Mazatlan FC | 17 | 6 | 3 | 8 | 14 | 39 | -25 | 21 | B19:00 | 20/11/20 | R 17 Mazatlan FC 1 Atletico San Luis 1 M20:00 | 14/11/20 | R 16 Pumas Unam 1 Mazatlan FC 0 G05:00 | 10/11/20 | R 15 Mazatlan FC 1 Club Tijuana de Caliente 0 B06:00 | 06/11/20 | R 14 Club Santos Laguna 1 Mazatlan FC 1 G19:00 | 31/10/20 | R 13 Mazatlan FC 2 Cruz Azul 0 M01:00 | 20/10/20 | R 12 CF Pachuca 3 Mazatlan FC 0 |
| 11 | |  Atletico San Luis | 17 | 5 | 2 | 10 | 22 | 30 | -8 | 17 | B19:00 | 20/11/20 | R 17 Mazatlan FC 1 Atletico San Luis 1 G02:00 | 16/11/20 | R 16 Atletico San Luis 2 Club Necaxa 0 M04:00 | 10/11/20 | R 15 Club Santos Laguna 2 Atletico San Luis 1 G05:00 | 06/11/20 | R 14 Atletico San Luis 2 Club Leon 1 M04:00 | 03/11/20 | R 13 Club Tijuana de Caliente 2 Atletico San Luis 0 B01:00 | 19/10/20 | R 12 Atletico San Luis 2 CD Guadalajara 2 |
| 12 | |  Puebla FC | 17 | 4 | 5 | 8 | 12 | 23 | -11 | 17 | G21:00 | 19/11/20 | R 17 Puebla FC 3 FC Juarez 0 B02:00 | 14/11/20 | R 16 Queretaro FC 1 Puebla FC 1 M21:00 | 08/11/20 | R 15 Puebla FC 0 CD Guadalajara 5 G00:45 | 05/11/20 | R 14 Cruz Azul 0 Puebla FC 1 M21:00 | 01/11/20 | R 13 Puebla FC 0 CF Tigres UANL 3 B20:00 | 17/10/20 | R 12 Puebla FC 0 Club Necaxa 0 |
| 13 | |  Club Leon | 17 | 4 | 4 | 9 | 21 | 31 | -10 | 16 | G02:00 | 20/11/20 | R 17 Club Leon 3 Pumas Unam 2 G21:00 | 15/11/20 | R 16 Deportivo Toluca FC 1 Club Leon 3 B06:00 | 10/11/20 | R 15 Club Leon 1 Cruz Azul 1 M05:00 | 06/11/20 | R 14 Atletico San Luis 2 Club Leon 1 M00:45 | 30/10/20 | R 13 Club Leon 1 Queretaro FC 3 M17:30 | 18/10/20 | R 12 CF Tigres UANL 3 Club Leon 1 |
| 14 | |  Cruz Azul | 17 | 3 | 5 | 9 | 14 | 24 | -10 | 14 | G01:00 | 21/11/20 | R 17 Queretaro FC 1 Cruz Azul 2 B18:00 | 14/11/20 | R 16 Cruz Azul 0 Club Santos Laguna 0 B06:00 | 10/11/20 | R 15 Club Leon 1 Cruz Azul 1 M00:45 | 05/11/20 | R 14 Cruz Azul 0 Puebla FC 1 M19:00 | 31/10/20 | R 13 Mazatlan FC 2 Cruz Azul 0 M00:00 | 19/10/20 | R 12 Cruz Azul 1 Deportivo Toluca FC 3 |
| 15 | |  Deportivo Toluca FC | 17 | 4 | 1 | 12 | 16 | 29 | -13 | 13 | M04:00 | 20/11/20 | R 17 Club Santos Laguna 2 Deportivo Toluca FC 0 M21:00 | 15/11/20 | R 16 Deportivo Toluca FC 1 Club Leon 3 M02:00 | 09/11/20 | R 15 Club Necaxa 2 Deportivo Toluca FC 1 M00:45 | 06/11/20 | R 14 Deportivo Toluca FC 1 Club America 2 M21:00 | 31/10/20 | R 13 Deportivo Toluca FC 1 Atlas FC 3 G00:00 | 19/10/20 | R 12 Cruz Azul 1 Deportivo Toluca FC 3 |
| 16 | |  Club Tijuana de Caliente | 17 | 3 | 3 | 11 | 16 | 31 | -15 | 12 | G02:00 | 20/11/20 | R 17 Club Necaxa 1 Club Tijuana de Caliente 2 G06:00 | 17/11/20 | R 16 Club Tijuana de Caliente 4 FC Juarez 1 M05:00 | 10/11/20 | R 15 Mazatlan FC 1 Club Tijuana de Caliente 0 M19:30 | 05/11/20 | R 14 CD Guadalajara 3 Club Tijuana de Caliente 0 G04:00 | 03/11/20 | R 13 Club Tijuana de Caliente 2 Atletico San Luis 0 B03:00 | 20/10/20 | R 12 Club Tijuana de Caliente 0 Pumas Unam 0 |
| 17 | |  FC Juarez | 17 | 3 | 2 | 12 | 13 | 44 | -31 | 11 | M21:00 | 19/11/20 | R 17 Puebla FC 3 FC Juarez 0 M06:00 | 17/11/20 | R 16 Club Tijuana de Caliente 4 FC Juarez 1 M03:00 | 10/11/20 | R 15 FC Juarez 0 CF Tigres UANL 4 B04:00 | 06/11/20 | R 14 CF Pachuca 2 FC Juarez 2 M03:00 | 03/11/20 | R 13 FC Juarez 0 Club America 1 M18:00 | 18/10/20 | R 12 Atlas FC 5 FC Juarez 0 |
| 18 | |  Club Necaxa | 17 | 3 | 1 | 13 | 10 | 33 | -23 | 10 | M02:00 | 20/11/20 | R 17 Club Necaxa 1 Club Tijuana de Caliente 2 M02:00 | 16/11/20 | R 16 Atletico San Luis 2 Club Necaxa 0 G02:00 | 09/11/20 | R 15 Club Necaxa 2 Deportivo Toluca FC 1 M21:00 | 05/11/20 | R 14 Pumas Unam 4 Club Necaxa 0 M01:00 | 02/11/20 | R 13 Club Necaxa 2 Club Santos Laguna 4 B20:00 | 17/10/20 | R 12 Puebla FC 0 Club Necaxa 0 |
