| 1 | |  Kelty Hearts FC | 36 | 24 | 9 | 3 | 68 | 28 | 40 | 81 | G17:00 | 30/04/22 | R 36  Annan Athletic FC 1 Kelty Hearts FC 2 B17:00 | 23/04/22 | R 35 Kelty Hearts FC 1 Forfar Athletic FC 1 G17:00 | 16/04/22 | R 34 Stranraer 0 Kelty Hearts FC 3 B17:00 | 09/04/22 | R 33 Kelty Hearts FC 1 Stirling Albion FC 1 B21:45 | 01/04/22 | R 32 Edinburgh City FC 1 Kelty Hearts FC 1 G18:00 | 26/03/22 | R 31 Kelty Hearts FC 1 Stenhousemuir 0 |
| 2 | |  Forfar Athletic FC | 36 | 16 | 12 | 8 | 57 | 36 | 21 | 60 | B17:00 | 30/04/22 | R 36 Forfar Athletic FC 0 Stenhousemuir 0 B17:00 | 23/04/22 | R 35 Kelty Hearts FC 1 Forfar Athletic FC 1 G17:00 | 16/04/22 | R 34 Forfar Athletic FC 5 Annan Athletic FC 1 M17:00 | 09/04/22 | R 33 Edinburgh City FC 2 Forfar Athletic FC 0 G17:00 | 02/04/22 | R 32 Stranraer 0 Forfar Athletic FC 2 B18:00 | 26/03/22 | R 31 Forfar Athletic FC 1 Cowdenbeath 1 |
| 3 | |  Annan Athletic FC | 36 | 18 | 5 | 13 | 64 | 51 | 13 | 59 | M17:00 | 30/04/22 | R 36 Annan Athletic FC 1 Kelty Hearts FC 2 M21:45 | 22/04/22 | R 35 Edinburgh City FC 2 Annan Athletic FC 1 M17:00 | 16/04/22 | R 34 Forfar Athletic FC 5 Annan Athletic FC 1 M17:00 | 09/04/22 | R 33 Annan Athletic FC 2 Cowdenbeath 3 G17:00 | 02/04/22 | R 32 Stenhousemuir 0 Annan Athletic FC 1 M18:00 | 26/03/22 | R 31 Annan Athletic FC 2 Albion Rovers FC 4 |
| 4 | |  Edinburgh City FC | 36 | 14 | 10 | 12 | 43 | 49 | -6 | 52 | M17:00 | 30/04/22 | R 36 Stirling Albion FC 5 Edinburgh City FC 0 G21:45 | 22/04/22 | R 35 Edinburgh City FC 2 Annan Athletic FC 1 B17:00 | 16/04/22 | R 34 Cowdenbeath 0 Edinburgh City FC 0 G17:00 | 09/04/22 | R 33 Edinburgh City FC 2 Forfar Athletic FC 0 B21:45 | 01/04/22 | R 32 Edinburgh City FC 1 Kelty Hearts FC 1 M18:00 | 26/03/22 | R 31 Elgin City FC 2 Edinburgh City FC 0 |
| 5 | |  Stenhousemuir | 36 | 13 | 10 | 13 | 47 | 46 | 1 | 49 | B17:00 | 30/04/22 | R 36 Forfar Athletic FC 0 Stenhousemuir 0 M17:00 | 23/04/22 | R 35 Stenhousemuir 1 Stranraer 3 G17:00 | 16/04/22 | R 34 Stenhousemuir 4 Albion Rovers FC 1 G17:00 | 09/04/22 | R 33 Elgin City FC 0 Stenhousemuir 2 M17:00 | 02/04/22 | R 32 Stenhousemuir 0 Annan Athletic FC 1 M18:00 | 26/03/22 | R 31 Kelty Hearts FC 1 Stenhousemuir 0 |
| 6 | |  Stranraer | 36 | 13 | 8 | 15 | 50 | 54 | -4 | 47 | G17:00 | 30/04/22 | R 36 Stranraer 2 Elgin City FC 0 G17:00 | 23/04/22 | R 35 Stenhousemuir 1 Stranraer 3 M17:00 | 16/04/22 | R 34 Stranraer 0 Kelty Hearts FC 3 G17:00 | 09/04/22 | R 33 Albion Rovers FC 0 Stranraer 5 M17:00 | 02/04/22 | R 32 Stranraer 0 Forfar Athletic FC 2 M18:00 | 26/03/22 | R 31 Stirling Albion FC 1 Stranraer 0 |
| 7 | |  Stirling Albion FC | 36 | 11 | 9 | 16 | 41 | 46 | -5 | 42 | G17:00 | 30/04/22 | R 36 Stirling Albion FC 5 Edinburgh City FC 0 B17:00 | 23/04/22 | R 35 Albion Rovers FC 1 Stirling Albion FC 1 M17:00 | 16/04/22 | R 34 Stirling Albion FC 0 Elgin City FC 2 B17:00 | 09/04/22 | R 33 Kelty Hearts FC 1 Stirling Albion FC 1 B17:00 | 02/04/22 | R 32 Cowdenbeath 0 Stirling Albion FC 0 G18:00 | 26/03/22 | R 31 Stirling Albion FC 1 Stranraer 0 |
| 8 | |  Albion Rovers FC | 36 | 10 | 9 | 17 | 37 | 58 | -21 | 39 | G17:00 | 30/04/22 | R 36 Cowdenbeath 0 Albion Rovers FC 1 B17:00 | 23/04/22 | R 35 Albion Rovers FC 1 Stirling Albion FC 1 M17:00 | 16/04/22 | R 34 Stenhousemuir 4 Albion Rovers FC 1 M17:00 | 09/04/22 | R 33 Albion Rovers FC 0 Stranraer 5 B17:00 | 02/04/22 | R 32 Albion Rovers FC 0 Elgin City FC 0 G18:00 | 26/03/22 | R 31 Annan Athletic FC 2 Albion Rovers FC 4 |
| 9 | |  Elgin City FC | 36 | 9 | 10 | 17 | 33 | 51 | -18 | 37 | M17:00 | 30/04/22 | R 36 Stranraer 2 Elgin City FC 0 M17:00 | 23/04/22 | R 35 Elgin City FC 1 Cowdenbeath 4 G17:00 | 16/04/22 | R 34 Stirling Albion FC 0 Elgin City FC 2 M17:00 | 09/04/22 | R 33 Elgin City FC 0 Stenhousemuir 2 B17:00 | 02/04/22 | R 32 Albion Rovers FC 0 Elgin City FC 0 G18:00 | 26/03/22 | R 31 Elgin City FC 2 Edinburgh City FC 0 |
| 10 | |  Cowdenbeath | 36 | 7 | 8 | 21 | 28 | 49 | -21 | 29 | M17:00 | 30/04/22 | R 36 Cowdenbeath 0 Albion Rovers FC 1 G17:00 | 23/04/22 | R 35 Elgin City FC 1 Cowdenbeath 4 B17:00 | 16/04/22 | R 34 Cowdenbeath 0 Edinburgh City FC 0 G17:00 | 09/04/22 | R 33 Annan Athletic FC 2 Cowdenbeath 3 |
