| 1 | |  FC Victoria Bardar | 22 | 15 | 4 | 3 | 51 | 24 | 27 | 49 | G16:00 | 08/04/22 | R 17  Olimp Comrat 1 FC Victoria Bardar 2 G16:00 | 16/04/22 | R 18 FC Victoria Bardar 3 FC Cahul 2005 0 G16:00 | 23/04/22 | R 19 FC Speranis Nisporeni 0 FC Victoria Bardar 4 G16:00 | 29/04/22 | R 20 FC Victoria Bardar 5 FC Iskra Stali Ribnita 1 G17:00 | 07/05/22 | R 21 FC Victoria Bardar 3 Fcm Ungheni 1 G17:00 | 13/05/22 | R 22 FC Sucleia 2 FC Victoria Bardar 5 |
| 2 | |  FC Sheriff Tiraspol 2 | 21 | 15 | 3 | 3 | 49 | 15 | 34 | 48 | G16:00 | 15/04/22 | R 18 FC Sheriff Tiraspol 2 4 CSF Spartanii Selemet 1 G16:00 | 26/04/22 | R 19 Olimp Comrat 1 FC Sheriff Tiraspol 2 2 G00:00 | 30/04/22 | R 20 FC Sheriff Tiraspol 2 3 FC Cahul 2005 0 G17:00 | 06/05/22 | R 21 FC Speranis Nisporeni 0 FC Sheriff Tiraspol 2 3 B17:00 | 10/05/22 | R 17 Dacia Buiucani 0 FC Sheriff Tiraspol 2 0 G17:00 | 13/05/22 | R 22 FC Sheriff Tiraspol 2 3 FC Iskra Stali Ribnita 1 |
| 3 | |  Dacia Buiucani | 21 | 14 | 5 | 2 | 58 | 15 | 43 | 47 | G16:00 | 15/04/22 | R 18 Real Succes 0 Dacia Buiucani 2 G16:00 | 23/04/22 | R 19 Dacia Buiucani 6 FC Speranta Drochia 1 G16:00 | 29/04/22 | R 20 Fcm Ungheni 0 Dacia Buiucani 3 B17:00 | 07/05/22 | R 21 CSF Spartanii Selemet 1 Dacia Buiucani 1 B17:00 | 10/05/22 | R 17 Dacia Buiucani 0 FC Sheriff Tiraspol 2 0 G17:00 | 13/05/22 | R 22 Dacia Buiucani 3 Olimp Comrat 0 |
| 4 | |  CSF Spartanii Selemet | 22 | 13 | 5 | 4 | 46 | 26 | 20 | 44 | B16:00 | 09/04/22 | R 17 CSF Spartanii Selemet 1 FC Sucleia 1 M16:00 | 15/04/22 | R 18 FC Sheriff Tiraspol 2 4 CSF Spartanii Selemet 1 G16:00 | 22/04/22 | R 19 CSF Spartanii Selemet 6 Real Succes 0 G16:00 | 30/04/22 | R 20 FC Speranta Drochia 1 CSF Spartanii Selemet 4 B17:00 | 07/05/22 | R 21 CSF Spartanii Selemet 1 Dacia Buiucani 1 M17:00 | 13/05/22 | R 22 Fcm Ungheni 4 CSF Spartanii Selemet 1 |
| 5 | |  FC Speranis Nisporeni | 22 | 12 | 0 | 10 | 31 | 31 | 0 | 36 | G16:00 | 08/04/22 | R 17 FC Speranis Nisporeni 2 Fcm Ungheni 1 M16:00 | 16/04/22 | R 18 FC Iskra Stali Ribnita 2 FC Speranis Nisporeni 0 M16:00 | 23/04/22 | R 19 FC Speranis Nisporeni 0 FC Victoria Bardar 4 M16:00 | 29/04/22 | R 20 FC Sucleia 1 FC Speranis Nisporeni 0 M17:00 | 06/05/22 | R 21 FC Speranis Nisporeni 0 FC Sheriff Tiraspol 2 3 G17:00 | 13/05/22 | R 22 Real Succes 0 FC Speranis Nisporeni 2 |
| 6 | |  Olimp Comrat | 22 | 10 | 5 | 7 | 41 | 36 | 5 | 35 | M16:00 | 08/04/22 | R 17 Olimp Comrat 1 FC Victoria Bardar 2 G16:00 | 17/04/22 | R 18 FC Sucleia 1 Olimp Comrat 2 M16:00 | 26/04/22 | R 19 Olimp Comrat 1 FC Sheriff Tiraspol 2 2 B16:00 | 30/04/22 | R 20 Real Succes 1 Olimp Comrat 1 G17:00 | 06/05/22 | R 21 Olimp Comrat 2 FC Speranta Drochia 0 M17:00 | 13/05/22 | R 22 Dacia Buiucani 3 Olimp Comrat 0 |
| 7 | |  FC Sucleia | 22 | 8 | 3 | 11 | 34 | 40 | -6 | 27 | B16:00 | 09/04/22 | R 17 CSF Spartanii Selemet 1 FC Sucleia 1 M16:00 | 17/04/22 | R 18 FC Sucleia 1 Olimp Comrat 2 G00:00 | 23/04/22 | R 19 FC Cahul 2005 0 FC Sucleia 3 G16:00 | 29/04/22 | R 20 FC Sucleia 1 FC Speranis Nisporeni 0 G17:00 | 07/05/22 | R 21 FC Iskra Stali Ribnita 2 FC Sucleia 3 M17:00 | 13/05/22 | R 22 FC Sucleia 2 FC Victoria Bardar 5 |
| 8 | |  FC Iskra Stali Ribnita | 22 | 7 | 4 | 11 | 28 | 44 | -16 | 25 | G00:00 | 09/04/22 | R 17 FC Cahul 2005 0 FC Iskra Stali Ribnita 3 G16:00 | 16/04/22 | R 18 FC Iskra Stali Ribnita 2 FC Speranis Nisporeni 0 G16:00 | 23/04/22 | R 19 FC Iskra Stali Ribnita 3 Fcm Ungheni 1 M16:00 | 29/04/22 | R 20 FC Victoria Bardar 5 FC Iskra Stali Ribnita 1 M17:00 | 07/05/22 | R 21 FC Iskra Stali Ribnita 2 FC Sucleia 3 M17:00 | 13/05/22 | R 22 FC Sheriff Tiraspol 2 3 FC Iskra Stali Ribnita 1 |
| 8 | |  Iskra Ribnita | 4 | 1 | 1 | 2 | 7 | 10 | -3 | 4 | |
| 9 | |  Fcm Ungheni | 22 | 6 | 6 | 10 | 38 | 42 | -4 | 24 | M16:00 | 08/04/22 | R 17 FC Speranis Nisporeni 2 Fcm Ungheni 1 B16:00 | 16/04/22 | R 18 Fcm Ungheni 0 FC Speranta Drochia 0 M16:00 | 23/04/22 | R 19 FC Iskra Stali Ribnita 3 Fcm Ungheni 1 M16:00 | 29/04/22 | R 20 Fcm Ungheni 0 Dacia Buiucani 3 M17:00 | 07/05/22 | R 21 FC Victoria Bardar 3 Fcm Ungheni 1 G17:00 | 13/05/22 | R 22 Fcm Ungheni 4 CSF Spartanii Selemet 1 |
| 10 | |  Real Succes | 22 | 5 | 3 | 14 | 22 | 45 | -23 | 18 | M16:00 | 09/04/22 | R 17 FC Speranta Drochia 2 Real Succes 1 M16:00 | 15/04/22 | R 18 Real Succes 0 Dacia Buiucani 2 M16:00 | 22/04/22 | R 19 CSF Spartanii Selemet 6 Real Succes 0 B16:00 | 30/04/22 | R 20 Real Succes 1 Olimp Comrat 1 G00:00 | 07/05/22 | R 21 FC Cahul 2005 0 Real Succes 3 M17:00 | 13/05/22 | R 22 Real Succes 0 FC Speranis Nisporeni 2 |
| 11 | |  FC Speranta Drochia | 22 | 4 | 4 | 14 | 20 | 48 | -28 | 16 | G16:00 | 09/04/22 | R 17 FC Speranta Drochia 2 Real Succes 1 B16:00 | 16/04/22 | R 18 Fcm Ungheni 0 FC Speranta Drochia 0 M16:00 | 23/04/22 | R 19 Dacia Buiucani 6 FC Speranta Drochia 1 M16:00 | 30/04/22 | R 20 FC Speranta Drochia 1 CSF Spartanii Selemet 4 M17:00 | 06/05/22 | R 21 Olimp Comrat 2 FC Speranta Drochia 0 G00:00 | 13/05/22 | R 22 FC Speranta Drochia 3 FC Cahul 2005 0 |
| 12 | |  FC Cahul 2005 | 22 | 0 | 2 | 20 | 6 | 58 | -52 | 2 | M00:00 | 09/04/22 | R 17 FC Cahul 2005 0 FC Iskra Stali Ribnita 3 M16:00 | 16/04/22 | R 18 FC Victoria Bardar 3 FC Cahul 2005 0 M00:00 | 23/04/22 | R 19 FC Cahul 2005 0 FC Sucleia 3 M00:00 | 30/04/22 | R 20 FC Sheriff Tiraspol 2 3 FC Cahul 2005 0 M00:00 | 07/05/22 | R 21 FC Cahul 2005 0 Real Succes 3 M00:00 | 13/05/22 | R 22 FC Speranta Drochia 3 FC Cahul 2005 0 |
