| 1 | |  Airbus UK Broughton | 28 | 23 | 3 | 2 | 85 | 23 | 62 | 72 | G17:00 | 19/03/22 | R 28  Llanrhaedr-ym-Mochnant FC 1 Airbus UK Broughton 4 G17:30 | 26/03/22 | R 27 Prestatyn Town 0 Airbus UK Broughton 2 G21:45 | 01/04/22 | R 29 Airbus UK Broughton 1 Llandudno FC 0 G16:30 | 15/04/22 | R 19 Airbus UK Broughton 4 Gresford Athletic 2 M16:30 | 18/04/22 | R 20 Holywell Town 3 Airbus UK Broughton 2 B16:30 | 23/04/22 | R 30 Guilsfield FC 0 Airbus UK Broughton 0 |
| 2 | |  Llandudno FC | 28 | 20 | 3 | 5 | 55 | 21 | 34 | 63 | G22:30 | 11/03/22 | R 26 Llandudno FC 3 Colwyn Bay 0 B17:30 | 19/03/22 | R 28 Holyhead Hotspur 1 Llandudno FC 1 G17:30 | 26/03/22 | R 27 Buckley Town 1 Llandudno FC 2 M21:45 | 01/04/22 | R 29 Airbus UK Broughton 1 Llandudno FC 0 M16:30 | 18/04/22 | R 20 Gresford Athletic 2 Llandudno FC 0 G16:30 | 23/04/22 | R 30 Llandudno FC 6 Llangefni Town 1 |
| 3 | |  Guilsfield FC | 28 | 14 | 10 | 4 | 51 | 24 | 27 | 52 | G22:30 | 22/03/22 | R 26 Guilsfield FC 3 Llanidloes Town 0 M17:30 | 26/03/22 | R 27 Colwyn Bay 3 Guilsfield FC 1 B16:30 | 02/04/22 | R 28 Guilsfield FC 1 Llangefni Town 1 G16:30 | 09/04/22 | R 29 Prestatyn Town 0 Guilsfield FC 2 G16:30 | 15/04/22 | R 19 Guilsfield FC 4 Llanrhaedr-ym-Mochnant FC 0 B16:30 | 23/04/22 | R 30 Guilsfield FC 0 Airbus UK Broughton 0 |
| 4 | |  Holywell Town | 28 | 15 | 5 | 8 | 68 | 36 | 32 | 50 | G17:30 | 26/03/22 | R 27 Llangefni Town 0 Holywell Town 3 M16:30 | 02/04/22 | R 17 Holywell Town 0 Colwyn Bay 1 M21:30 | 08/04/22 | R 29 Holywell Town 2 Conwy Borough 3 G16:30 | 15/04/22 | R 19 Holywell Town 4 Prestatyn Town 1 G16:30 | 18/04/22 | R 20 Holywell Town 3 Airbus UK Broughton 2 G16:30 | 23/04/22 | R 30 Penrhyncoch 1 Holywell Town 3 |
| 5 | |  Ruthin Town | 28 | 15 | 4 | 9 | 51 | 34 | 17 | 49 | G17:30 | 19/03/22 | R 19 Ruthin Town 2 Buckley Town 0 M17:00 | 26/03/22 | R 27 Gresford Athletic 1 Ruthin Town 0 G16:30 | 02/04/22 | R 24 Ruthin Town 5 Holyhead Hotspur 0 B16:30 | 09/04/22 | R 29 Llangefni Town 1 Ruthin Town 1 G16:30 | 18/04/22 | R 20 Prestatyn Town 0 Ruthin Town 3 G16:30 | 23/04/22 | R 30 Conwy Borough 1 Ruthin Town 3 |
| 6 | |  Colwyn Bay | 28 | 15 | 3 | 10 | 60 | 40 | 20 | 48 | M17:30 | 05/03/22 | R 25 Colwyn Bay 0 Airbus UK Broughton 3 M22:30 | 11/03/22 | R 26 Llandudno FC 3 Colwyn Bay 0 G17:30 | 26/03/22 | R 27 Colwyn Bay 3 Guilsfield FC 1 G16:30 | 02/04/22 | R 17 Holywell Town 0 Colwyn Bay 1 G16:30 | 09/04/22 | R 29 Colwyn Bay 5 Llanrhaedr-ym-Mochnant FC 0 B16:30 | 15/04/22 | R 19 Conwy Borough 1 Colwyn Bay 1 |
| 7 | |  Holyhead Hotspur | 28 | 11 | 8 | 9 | 41 | 34 | 7 | 41 | B17:30 | 19/03/22 | R 28 Holyhead Hotspur 1 Llandudno FC 1 G17:30 | 26/03/22 | R 27 Holyhead Hotspur 2 Llanidloes Town 1 M16:30 | 02/04/22 | R 24 Ruthin Town 5 Holyhead Hotspur 0 B16:30 | 09/04/22 | R 29 Buckley Town 2 Holyhead Hotspur 2 G16:30 | 15/04/22 | R 19 Llangefni Town 0 Holyhead Hotspur 5 G16:30 | 23/04/22 | R 30 Holyhead Hotspur 4 Prestatyn Town 0 |
| 8 | |  Buckley Town | 28 | 11 | 7 | 10 | 48 | 48 | 0 | 40 | M17:30 | 19/03/22 | R 19 Ruthin Town 2 Buckley Town 0 M17:30 | 26/03/22 | R 27 Buckley Town 1 Llandudno FC 2 G21:30 | 01/04/22 | R 28 Buckley Town 2 Gresford Athletic 1 B16:30 | 09/04/22 | R 29 Buckley Town 2 Holyhead Hotspur 2 M16:30 | 18/04/22 | R 20 Buckley Town 1 Conwy Borough 4 G16:30 | 23/04/22 | R 30 Llanrhaedr-ym-Mochnant FC 0 Buckley Town 3 |
| 9 | |  Penrhyncoch | 28 | 9 | 8 | 11 | 39 | 57 | -18 | 35 | M17:30 | 12/03/22 | R 26 Penrhyncoch 0 Holyhead Hotspur 1 G17:30 | 26/03/22 | R 27 Llanrhaedr-ym-Mochnant FC 0 Penrhyncoch 3 B16:30 | 02/04/22 | R 28 Penrhyncoch 1 Conwy Borough 1 M16:30 | 09/04/22 | R 29 Gresford Athletic 4 Penrhyncoch 2 G16:30 | 15/04/22 | R 19 Penrhyncoch 2 Llanidloes Town 0 M16:30 | 23/04/22 | R 30 Penrhyncoch 1 Holywell Town 3 |
| 10 | |  Conwy Borough | 28 | 8 | 8 | 12 | 42 | 59 | -17 | 32 | M22:30 | 04/03/22 | R 25 Holyhead Hotspur 2 Conwy Borough 0 B16:30 | 02/04/22 | R 28 Penrhyncoch 1 Conwy Borough 1 G21:30 | 08/04/22 | R 29 Holywell Town 2 Conwy Borough 3 B16:30 | 15/04/22 | R 19 Conwy Borough 1 Colwyn Bay 1 G16:30 | 18/04/22 | R 20 Buckley Town 1 Conwy Borough 4 M16:30 | 23/04/22 | R 30 Conwy Borough 1 Ruthin Town 3 |
| 11 | |  Gresford Athletic | 28 | 8 | 7 | 13 | 39 | 42 | -3 | 31 | G17:00 | 26/03/22 | R 27 Gresford Athletic 1 Ruthin Town 0 M21:30 | 01/04/22 | R 28 Buckley Town 2 Gresford Athletic 1 G16:30 | 09/04/22 | R 29 Gresford Athletic 4 Penrhyncoch 2 M16:30 | 15/04/22 | R 19 Airbus UK Broughton 4 Gresford Athletic 2 G16:30 | 18/04/22 | R 20 Gresford Athletic 2 Llandudno FC 0 M16:30 | 23/04/22 | R 30 Llanidloes Town 3 Gresford Athletic 1 |
| 12 | |  Llanidloes Town | 28 | 7 | 7 | 14 | 44 | 59 | -15 | 28 | M22:30 | 22/03/22 | R 26 Guilsfield FC 3 Llanidloes Town 0 M17:30 | 26/03/22 | R 27 Holyhead Hotspur 2 Llanidloes Town 1 G16:30 | 02/04/22 | R 23 Llanidloes Town 4 Prestatyn Town 0 M16:30 | 15/04/22 | R 19 Penrhyncoch 2 Llanidloes Town 0 G16:30 | 18/04/22 | R 13 Llanrhaedr-ym-Mochnant FC 1 Llanidloes Town 6 G16:30 | 23/04/22 | R 30 Llanidloes Town 3 Gresford Athletic 1 |
| 13 | |  Prestatyn Town | 28 | 5 | 5 | 18 | 34 | 68 | -34 | 20 | M17:30 | 26/03/22 | R 27 Prestatyn Town 0 Airbus UK Broughton 2 M16:30 | 02/04/22 | R 23 Llanidloes Town 4 Prestatyn Town 0 M16:30 | 09/04/22 | R 29 Prestatyn Town 0 Guilsfield FC 2 M16:30 | 15/04/22 | R 19 Holywell Town 4 Prestatyn Town 1 M16:30 | 18/04/22 | R 20 Prestatyn Town 0 Ruthin Town 3 M16:30 | 23/04/22 | R 30 Holyhead Hotspur 4 Prestatyn Town 0 |
| 14 | |  Llangefni Town | 28 | 3 | 6 | 19 | 19 | 70 | -51 | 15 | G17:30 | 05/03/22 | R 25 Llangefni Town 2 Gresford Athletic 1 M17:30 | 26/03/22 | R 27 Llangefni Town 0 Holywell Town 3 B16:30 | 02/04/22 | R 28 Guilsfield FC 1 Llangefni Town 1 B16:30 | 09/04/22 | R 29 Llangefni Town 1 Ruthin Town 1 M16:30 | 15/04/22 | R 19 Llangefni Town 0 Holyhead Hotspur 5 M16:30 | 23/04/22 | R 30 Llandudno FC 6 Llangefni Town 1 |
| 15 | |  Llanrhaedr-ym-Mochnant FC | 28 | 2 | 4 | 22 | 23 | 84 | -61 | 10 | M17:00 | 19/03/22 | R 28 Llanrhaedr-ym-Mochnant FC 1 Airbus UK Broughton 4 M17:30 | 26/03/22 | R 27 Llanrhaedr-ym-Mochnant FC 0 Penrhyncoch 3 M16:30 | 09/04/22 | R 29 Colwyn Bay 5 Llanrhaedr-ym-Mochnant FC 0 M16:30 | 15/04/22 | R 19 Guilsfield FC 4 Llanrhaedr-ym-Mochnant FC 0 M16:30 | 18/04/22 | R 13 Llanrhaedr-ym-Mochnant FC 1 Llanidloes Town 6 M16:30 | 23/04/22 | R 30 Llanrhaedr-ym-Mochnant FC 0 Buckley Town 3 |
| 16 | |  Bangor City | 14 | 4 | 3 | 7 | 28 | 30 | -2 | 0 | |
