European ruling body UEFA has launched an investigation after Sevilla goalkeeper Marko Dmitrovic was punched by a PSV fan during Thursday's Europa League match.
The on-field skirmish came near the end of the game, which saw PSV win 2-0 but suffer a 3-2 aggregate elimination against their LaLiga opponents.
Dmitrovic pinned down the pitch invader and held him to the ground before security arrived to escort him away.
UEFA is understood to have opened a case following the incident, which has been condemned by PSV, who said the fan should not have been in the stadium in the first place.
The Dutch club said in a statement: "PSV strongly condemn the incident on Thursday evening when a man invaded the pitch and confronted the goalkeeper. The person involved had already been handed a stadium ban."
PSV general manager Marcel Brands said: "This is not what we stand for at PSV. We feel ashamed and there is no place for that type of behaviour.
"We will consult the organizations involved to discuss how we can enforce stadium bans better, hopefully through reporting obligations. All PSV supporter organizations, who cheered on their team last night, unanimously and explicitly distance themselves from this disgraceful pitch invasion."
PSV said they would "await the investigations into the pitch invader made by the police and look to recover any financial damages."
Sevilla have been drawn to face Turkish Super Lig outfit Fenerbahce in the last 16 stage.
Six-time champions Sevilla are looking to extend their record haul in the competition, which began in its previous guise as the UEFA Cup, having last lifted the trophy in 2020 against Inter.